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Table 2 Number and incidence of osteoporosis-related fractures in RA patients and matched controls

From: Osteoporosis-related fractures in men and women with established and early rheumatoid arthritis: predictors and risk compared with the general population

  

Men

Women

All

Fracture

Total cohort

RA patients

Controls

RA patients

Controls

RA patients

Controls

Hip

n (%)

43 (8.5)

92 (5.1)

147 (11.2)

463 (9.3)

190 (10.5)

555 (8.2)

 

Incidence/1000 PY (95% CI)

6.56

(4.75; 8.84)

3.63

(2.93; 4.45)

8.16

(6.89; 9.59)

6.21

(5.66; 6.81)

7.73

(6.67; 8.91)

5.56

(5.11; 6.04)

Fractures in total

n (%)

51 (10.2)

118 (6.6)

202 (15.8)

602 (12.3)

253 (14.2)

720 (10.8)

 

Incidence/1000 PY (95% CI)

7.86

(5.85; 10.33)

4.70

(3.89; 5.62)

11.58

(10.04; 13.29)

8.27

(7.62; 8.95)

10.57

(9.31; 11.96)

7.35

(6.82; 7.91)

Fracture

Early RA*

RA patients

Controls

RA patients

Controls

RA patients

Controls

Hip

n (%)

6 (3.0)

24 (3.0)

16 (3.2)

68 (3.4)

22 (3.1)

92 (3.3)

 

Incidence/1000 PY (95% CI)

3.41

(1.25; 7.43)

3.51

(2.25; 5.22)

3.48

(1.22; 5.64)

3.73

(2.90; 4.73)

3.46

(2.17; 5.24)

3.67

(2.96; 4.50)

Fractures in total

n (%)

7 (3.4)

33 (4.2)

29 (5.8)

101 (5.1)

36 (5.1)

134 (4.8)

 

Incidence/1000 PY (95% CI)

4.00

(1.61; 8.25)

4.89

(3.36; 6.86)

6.40

(4.29; 9.19)

5.64

(4.60; 6.86)

5.73

(4.02; 7.94)

5.44

(4.55; 6.44)

Fracture

Established RA**

RA patients

Controls

RA patients

Controls

RA patients

Controls

Hip

n (%)

31 (14.0)

39 (5.4)

82 (14.0)

257 (12.2)

113 (14.0)

296 (10.5)

 

Incidence/1000 PY (95% CI)

11.35

(7.71; 16.11)

3.65

(2.60; 4.99)

10.79

(8.58; 13.40)

7.84

(6.91; 8.86)

10.94

(9.02; 13.15)

6.81

(6.06; 7.63)

Fractures in total

n (%)

34 (15.5)

46 (6.4)

106 (18.9)

324 (15.6)

140 (17.9)

370 (13.3)

 

Incidence/1000 PY (95% CI)

12.55

(8.69; 17.53)

4.32

(3.16; 5.76)

14.64

(11.99; 17.71)

10.15

(9.07; 11.32)

14.07

(11.84; 16.60)

8.69

(7.83; 9.62)

  1. RA: Rheumatoid Arthritis; n: Number; PY: Person Years; CI: Confidence Interval
  2. *Early RA: newly diagnosed (within 1 year) patients in 1997 or later with follow-up time maximal 10 years
  3. **Established RA: patients with RA diagnosis for ≥ 5 years at study start (1997)