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Table 3 IRR and HR for osteoporosis-related fractures in RA patients compared with matched controls

From: Osteoporosis-related fractures in men and women with established and early rheumatoid arthritis: predictors and risk compared with the general population

 

INCIDENCE RATE RATIO (95% CI)

HAZARD RATIO (95% CI)

Total cohort

Men

Women

All

Men

Women

All

Hip fracture

1.81

(1.23; 2.61)

1.31

(1.08; 1.58)

1.39

(1.17; 1.64)

1.68

(1.05; 2.68)

1.41

(1.14; 1.75)

1.46

(1.20; 1.77)

Fractures in total

1.67

(1.18; 2.33)

1.40

(1.19; 1.64)

1.44

(1.24; 1.66)

1.55

(1.03; 2.34)

1.52

(1.27; 1.83)

1.53

(1.29; 1.81)

Early RA*

      

Hip fracture

0.97

(0.33; 2.46)

0.93

(0.50; 1.61)

0.94

(0.56; 1.50)

NA

0.85

(0.49; 1.49)

0.81

(0.50; 1.33)

Fractures in total

0.82

(0.31; 1.88)

1.13

(0.72; 1.72)

1.05

(0.71; 1.53)

NA

1.14

(0.74; 1.75)

1.01

(0.69; 1.49)

Established RA**

      

Hip fracture

3.11

(1.88; 5.06)

1.38

(1.06; 1.77)

1.61

(1.28; 2.00)

3.77

(1.79; 7.96)

1.76

(1.31; 2.38)

1.97

(1.50; 2.59)

Fractures in total

2.90

(1.81; 4.58)

1.44

(1.15; 1.80)

1.62

(1.32; 1.97)

2.99

(1.57; 5.70)

1.77

(1.36; 2.30)

1.91

(1.50; 2.43)

  1. Bold text indicates statistically significant results. IRR: Incidence Rate Ratio; HR: Hazard Ration; RA: Rheumatoid Arthritis; CI: Confidence Interval; NA: Not applicable due to < 10 events in patients with RA
  2. *Early RA: newly diagnosed (within 1 year) patients from the year of 1997 with follow-up time maximal 10 years
  3. **Established RA: patients with RA diagnosis for ≥ 5 years at study start (1997)