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Table 3 The comparison between different treatment groups

From: Correlation of serum subfatin, cthrc1, ctrp3, ctrp6 levels with disease indices in patients with axial spondyloarthritis

 

TNF-inhibitors

(n = 43)

cDMARD

(n = 18)

p-value

Age (years)

43 ± 9

34 ± 9

0.02

ESR (mm/hr)

14 [8–35]

21 [9–34]

0.72

CRP (mg/L)

2 [2–9]

4.4 [2–10]

0.61

Subfatin (ng/mL)

0.57 [0.4–0.8]

0.89 [0.6–1.7]

0.03

CTHRC1 (ng/mL)

54 [39–89]

71 [40–181]

0.33

CTRP3 (ng/mL)

1.9 [1.7-2]

2.2 [1.8-3]

0.03

CTRP6 (ng/mL)

1.92 [1.1–2.6]

2.85 [1.5–6.8]

0.03

IL-6 (pg/mL)

70 [55–80]

73 [55–138]

0.35

IL-17 (pg/mL)

19 [15–32]

33 [21–55]

0.04

TNF-α (pg/mL)

93 [76–128]

118 [97–163]

0.01

ASDAS-CRP

2.4 ± 1.0

2.8 ± 0.9

0.16

BASDAI

3.4 ± 1.8

4.1 ± 1.7

0.21

  1. *Data are given in median [25-75p] or mean ± SD
  2. **ESR: Erythrocyte sedimentation rate; CRP: C-reactive protein; CTHRC1: Collagen triple helix repeat-containing protein-1; CTRP3: C1q/TNF-related protein-3; CTRP6: C1q/TNF-related protein-6; TNF: Tumor necrosis factor; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; ASDAS-CRP: Ankylosing Spondylitis Disease Activity Score-CRP