Table 2 Summary of corticosteroid therapy BD patients with ON
Author, year | Patients No. | Highest daily corticosteroid dose before ON (mg/day) | Number of corticosteroid pulses before ON | Time between initial corticosteroid dose and ON (months) | Cumulative corticosteroid dose prior to ON (g) |
|---|---|---|---|---|---|
Atas et al., 2019 [7] | #1 | 64 | 1000 mg/month, 8 cycles | 24 | 18 |
#2 | 80 | 1000 mg/month, 8 cycles | 30 | 18.4 | |
#3 | 48 | 500 mg/q2w, 8 cycles | 27 | 14.2 | |
#4 | 80 | Single 500 mg infusion | 20 | 6 | |
#5 | 60 | 1000 mg/month, 5 cycles | 30 | 11 | |
#6 | 64 | 1000 mg for 3 consecutive days/2 cycles | 24 | 21 | |
#7 | 60 | 1000 mg/day, 3 cycles | 100 | 19 | |
#8 | 64 | 1000 mg for 7 consecutive days | 2 | 10 | |
#9 | 64 | 1000 mg/month, 8 cycles | 24 | 18 | |
Banicioiu-covei et al., 2019 [8] | 1 | na | na | Less than 12 months | na |
Chang et al., 2001 [10] | #1 | 0 | 0 | 0 | 0 |
#2 | na | na | 36 | na | |
Ersoz et al., 2013 [14] | 1 | na | na | na | na |
Essaadouni et al., 2017 [15] | 1 | na | na | 36 | na |
Faezi et al., 2018 [16] | 1 | na | 0 | 4 | na |
Lin et al., 2008 [17] | 1 | na | na | na | na |
Oktayoglu et al., 2012 [11] | 1 | na | na | 120 | na |
Polat et al., 2010 [9] | 1 | na | 0 | 7 | na |
Vaiopoulos et al., 2019 [18] | #1 & #2 & #3 | na | na | na | na |
Varoglu et al., 2017 [13] | 1 | na | methylprednisolone [5-day 1000 mg/day intravenous (IV) infusion] | 12 | na |
Yapar et al., 2001 [12] | 1 | na | na | na | na |
The present study | #1 | 60 | 5 | 15 | 15.24 |
#2 | 45 | 1 | 28 | -20.02 g before the first AVN -22.26 g before the second AVN | |
#3 | 30 | 0 | 12 | 5.74 | |
#4 | 30 | 0 | 7 | 5.88 | |
#5 | 30 | 0 | 6 | 5.04 | |
#6 | 30 | 0 | 90 | 17.57 | |
#7 | 30 | 0 | 24 | 3.56 | |
#8 | 75 | 0 | 11 | 5.81 | |
#9 | 60 | 0 | 19 | 17.57 | |
#10 | 30 | 0 | 12 | 5.42 | |
#11 | 30 | 0 | 12 | 7.56 | |
#12 | 30 | 5 | 40 | 22.92 | |
#13 | 40 | 0 | 8 | 7.28 | |
#14 | 40 | 0 | 108 | 45.43 |