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Table 3 Laboratory characteristics of RA patients

From: The study of serum muscarinic acetylcholine receptor subtype 3 (m3AChR)-Specific autoantibodies level in rheumatoid arthritis patients with secondary sjogren syndrome

Inflammatory markers

Group I

(n = 30)

Group II

(n = 30)

Control

(n = 30)

Post Hoc test

p-value

Sig. bet. Groups.

1st ESR (mm/h)

 Range

7.0–75.0

9.0–65.0

5.0–10.0

44.937*

< 0.001*

p1 = 0.513

p2 < 0.001*

p3 < 0.001*

 Median (IQR)

33.0

(20.0–40.0)

25.0

(18.0–37.0)

9.0

(8.0–10.0)

2nd ESR (mm/h)

 Range

18.0–100.0

20.0–110.0

10.0–20.0

46.762*

< 0.001*

p1 = 0.553

p2 < 0.001*

p3 < 0.001*

 Median (IQR)

60.0

(40.0–80.0)

50.0

(35.0–70.0)

18.0

(15.0–20.0)

CRP (mg/l)

 Range

1.10–98.0

3.0–314.0

2.0–8.0

40.385*

< 0.001*

p1 = 0.404,

p2 < 0.001*

p3 < 0.001*

 Median (IQR)

24.45

(11.3–50.4)

18.0

(10.0–42.6)

5.0

(4.0–6.0)

RF (IU/mL)

 Min. – Max.

6.0–512.0

1.0–240.0

1.0–20.0

55.101*

< 0.001*

p1 = 0.020*

p2 < 0.001*

p3 < 0.001*

 Median (IQR)

80.0

(64.0–208.0)

50.50

(8.0–64.0)

3.0

(2.0–6.0)

Anti CCP (u/mL)

 Min. – Max.

1.0–500.0

1.0–672.0

1.0–7.0

34.818*

< 0.001*

p1 = 0.005*

P2 < 0.001*

p3 < 0.001*

 Median (IQR)

118.0

(70.0–324.0)

70.50

(24.0–207.0)

4.0

(2.0–5.0)

Positive Anti-Ro/ SSA (n, %)

15(50)

0(0)

0(0)

--

--

--

Positive Anti-La/SSB (n, %)

5(16.7)

0(0)

0(0)

--

--

--

Positive both Anti-Ro/ SSA& Anti-La/SSB (n, %)

10(33.3)

0(0)

0(0)

--

--

--

m3AchR (ng/ml)

 Min. – Max.

16.08–32.89

14.32–33.79

14.18–25.98

26.640*

< 0.001*

p1 < 0.001*

p2 < 0.001*

p3 = 0.258

 Median (IQR)

27.38

(21.51–29.47)

18.42

(17.49–21.65)

17.26

(14.82–20.63)

  1. IQR: Inter quartile range, SD: Standard deviation, F: One way ANOVA test, pairwise comparison between. each 2 groups were done using Post Hoc Test (Tukey). p: p value for comparing between the three studied groups, p1: p value for comparing between Group I and Group II, p2: p value for comparing between Group I and control Group, p3: p value for comparing between Group II and control Group. *: Statistically significant at p ≤ 0.05, ESR: erythrocyte sedimentation rate, CRP: C- reactive protein, RF: rheumatoid factor, Anti-CCP: Anti cyclic citrullinated peptide, m3AChR: muscarinic acetylcholine receptor subtype 3 specific autoantibodies