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Table 2 Baseline clinical characteristics of RACER cohort segregated by RA disease activity

From: Cross-sectional association between social and demographic factors and disease activity in rheumatoid arthritis

All

Total n, %

High DAa, n, %

Low DA n, %

Chi-square p-value

729, 100%

326, 45%

403, 55%

CRP: Abnormal

241, 33%

170, 52%

71, 18%

 < 0.0001*

Disease duration

0–2 years

114, 16%

61, 19%

53, 13%

 

 > 2 and < 10 years

253, 35%

98, 30%

155, 38%

 

 > 10 years

360, 49%

167, 51%

193, 48%

0.0221*

Medication current use

Methotrexate

720, 98.8%

323, 99%

397, 99%

0.449

Leflunomide

72, 10%

35, 11%

37, 9%

NA

Biologic agent

275, 38%

95, 29%

180, 45%

1

Steroid

720, 98.8%

323, 99%

397, 99%

0.449

 

n, median (IQR)

Wilcoxon p-value

RF

683, 44 (20, 191)

305, 63 (21, 345)

378, 36 (20, 136)

0.0002*

Anti-CCPb

728, 41 (2, 206.5)

326, 45.3 (2, 224)

402, 35 (2, 196)

0.3972

IL-6

694, 2 (2, 9)

311, 5 (2, 12.3)

383, 2 (2, 6.4)

 < .0001*

  1. Number of missing for the above variables’ bivariate analyses are disease duration (missing N = 2); Methotrexate (missing N = 9); Leflunomide (missing N = 657); Biologic agent (missing N = 454); Steroid (missing N = 9)
  2. aDA: disease activity. High DS: DAS28-CRP > 3.1; Low DS: DAS28-CRP <  = 3
  3. bAnti-CCP, Anti-Cyclic Citrullinated Peptide antibodies
  4. *Significant at p < 0.05