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Table 1 Main characteristics of the included studies in the meta-analysis

From: Risk of venous thromboembolism in patients with rheumatoid arthritis: a meta-analysis of observational studies

First author and year

Design

Country

Period

Source of cases

Assessment of cases

Outcome

Assessment of outcomes

Quality score

Bacani 2012

Cohort

USA

1980–2007

EMR

ACR criteria

VTE, PE

MR + lab/imaging

9

Choi 2013

Cohort

UK

1986–2010

EMR

Diagnostic code + DMARD

VTE, DVT, PE

Hospital code + anticoagulant OR hospital code + DC/autopsy

9

Chung 2014

Cohort

Taiwan

1998–2008

Claims data

ACR criteria

DVT, PE

ICD-9 code

10

Holmqvist 2012

Cohort

Sweden

1997–2009

Registry

ACR criteria

VTE, DVT, PE

ICD-10 code

9

Johannesdottir 2012

Case-control

Denmark

1999–2009

Registry

ICD-8/ ICD-10 codes

VTE, DVT, PE

ICD 8–10

9

Kim 2013

Cohort

USA

2001–2008

Claims data

Two physician visits + ICD-9 code + DMARD

VTE, DVT, PE

ICD-9 code + anticoagulants

8

Li 2021

Cohort

Canada

1997–2009

Claims data

Two physician visits + ICD-9 code

VTE, DVT, PE

ICD-9/ ICD-10 + anticoagulants

9

Ramagopalan (a) 2011

Cohort

England, UK

1963–1998

EMR

ICD 7–10 code

VTE

ICD 7–10 code

6

Ramagopalan (b) 2011

Cohort

England, UK

1998–2008

EMR

ICD 7–10 code

VTE

ICD 7–10 code

6

Ramagopalan (c) 2011

Cohort

England, UK

1998–2009

EMR

ICD 7–10 code

VTE

ICD 7–10 code

6

Zoller 2012

Cohort

Sweden

1964–2008

EMR

ICD 7–10 code

PE

ICD 7–10 code

6

Galloway 2020

Cohort

England, UK

1999–2018

EMR

Diagnostic codes

VTE, DVT, PE

Diagnostic codes

8

Molander 2021

Cohort

Sweden

2006–2018

Registry

Diagnosis by clinician

VTE

ICD-10 code

6

Setyawan 2021

Cohort

USA

2014–2018

Claims data

ICD-9 and ICD-10

DVT, PE

Diagnosis by clinician

7

  1. Abbreviations: ACR = American College of Rheumatology; BC = British Columbia; DC = death certificate; DMARDs = disease modifying anti-rheumatic drugs; DVT = deep vein thrombosis; EMR = electronic medical records; ICD = International Classification of Diseases; MR = Medical record; NAV = not available; PE = pulmonary embolism; UK = United Kingdom; USA = United States of America; VTE = venous thromboembolism