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Table 2 Genotype and allele frequency of PTPN22 gene R620W functional variant in SLE patients and controls

From: High prevalence of protein tyrosine phosphatase non-receptor N22 gene functional variant R620W in systemic lupus erythematosus patients from Kuwait: implications for disease susceptibility

Genotype/Allele SLE patients
N = 126 (%)
Controls
N = 214 (%)
OR (95% CI)a P-value*
CC 81 (64.3) 180 (84.1) 0.34 (0.20–0.57) < 0.0001
CT 23 (18.3) 32 (15) 1.27 (0.70–2.28) 0.51
TT 22 (17.4) 2 (0.9) 22.42 (5.17–97.21) < 0.0001
Distribution of Alleles
C – allele 185/252 (73.4) 392/428 (91.6) 0.25 (0.16–0.39) < 0.0001
T – allele 67/252 (26.6) 36/428 (8.4) 3.94 (2.53–6.13) < 0.0001
  1. aOR, odds ratio at 95% confidence interval
  2. *P-values were considered significant when < 0.05