Takayasu arteritis is a rare large vessel vasculitis which predominantly affects young Asian females. Aortic regurgitation and heart failure are well described manifestations which are usually preceded by cons...
Authors: Nipun Lakshitha de Silva, Milinda Withana, Praveen Weeratunga, Prakash Priyadharshana and Inoshi Atukorala
There is growing evidence that it may be possible to identify people at high risk of developing rheumatoid arthritis (RA). Assuming that effective interventions were available, this could mean that treatments ...
Authors: Sarah Munro, Luke Spooner, Katherine Milbers, Marie Hudson, Cheryl Koehn and Mark Harrison
Behcet’s disease and Sjogren’s syndrome is an autoimmune disorder from which many systems of the body can suffer. Here we reported a patient with a history of Behcet’s disease and Sjogren’s syndrome in which R...
Authors: Fulong Xiao, Jun Zhang, Waner Wang, Xuehua Wang, Wei Zhang, Liyue Xu and Fang Han
Clinical response and remission are defined in multiple ways and measured with different instruments, resulting in substantial variation of the proportion of patients classified as being in remission. Therefor...
Authors: Samina A. Turk, Linda A. Rasch, Dirkjan van Schaardenburg, Willem F. Lems, Marjolein Sanberg, Lilian H. D. van Tuyl and Marieke M. ter Wee
Patients with metabolic syndrome (MetS) are at increased risk of asymptomatic hyperuricemia (i.e., elevated serum uric acid (SUA) level without gout) and cardiovascular disease. We conducted a cross-sectional ...
Authors: Seoyoung C. Kim, Marcelo F. Di Carli, Rajesh K. Garg, Kathleen Vanni, Penny Wang, Alyssa Wohlfahrt, Zhi Yu, Fengxin Lu, Anarosa Campos, Courtney F. Bibbo, Stacy Smith and Daniel H. Solomon
This study aimed to explore the beliefs of people with knee osteoarthritis (OA) about the disease, and how these beliefs had formed and what impact these beliefs had on activity participation, health behaviour...
Authors: Ben Darlow, Melanie Brown, Bronwyn Thompson, Ben Hudson, Rebecca Grainger, Eileen McKinlay and J. Haxby Abbott
This study analyzed visits for and factors associated with gout and gout medication treatment trends for the years 2007–2011 in the United States given the introduction of febuxostat, the first new treatment o...
Authors: Kristen E. Castro, Kaitlyn D. Corey, Diana L. Raymond, Michael R. Jiroutek and Melissa A. Holland
Systemic Sclerosis is a multifactorial autoimmune rheumatic disease characterized by inflammation, fibrosis, immune dysregulation and vascular dysfunction.
Authors: Annemarie Schorpion, Max Shenin, Robin Neubauer and Chris T. Derk
Cardiovascular disease (CVD) is markedly increased in patients with rheumatoid arthritis partly due to accelerated atherosclerosis from chronic inflammation. Traditional cardiovascular risk factors such as hyp...
Chronic pain, regional or widespread, is a frequent and multidimensional symptom in arthritis. There is still limited information on chronic pain in spondyloarthritis, which is important to recognize for adequ...
Authors: Elisabeth Mogard, Ann Bremander, Elisabet Lindqvist and Stefan Bergman
Pneumococcal vaccination is recommended to patients with rheumatoid arthritis (RA) and primary Sjögren’s syndrome (pSS). However, little is known whether the diseases influence pneumococcal vaccine response. T...
Authors: Per Nived, Tore Saxne, Pierre Geborek, Thomas Mandl, Lillemor Skattum and Meliha C. Kapetanovic
Pharmacotherapy is paramount to the management of systemic autoimmune rheumatic diseases (SARDs), yet there is sub-optimal adherence and limited adherence interventions. To understand how to better support pat...
Authors: Hans Haag, Tim Liang, J. Antonio Avina-Zubieta and Mary A. De Vera
DAS28 is interpreted as the inflammatory disease activity of RA. Non-inflammatory pain mechanisms can confound assessment. We aimed to examine the use of DAS28 components or DAS28-derived measures that have be...
Authors: Daniel F. McWilliams, Patrick D. W. Kiely, Adam Young, Nalinie Joharatnam, Deborah Wilson and David A. Walsh
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease which involves the loss of self-tolerance with hyperactivation of autoreactive T- and B-cells. Protein tyrosine phosphatase non-receptor...
Authors: Adel M. Al-Awadhi, Mohammad Z. Haider, Jalaja Sukumaran and Sowmya Balakrishnan
Methotrexate (MTX) is well known to affect folic acid metabolism, so MTX treatment can result in alterations of mean corpuscular volume (MCV), which may impact on red cell distribution width (RDW), as MCV leve...
Authors: Julia Held, Birgit Mosheimer-Feistritzer, Johann Gruber, Erich Mur and Günter Weiss
Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. Children with JIA are at risk of intraocular inflammation (uveitis). In the initial stages of mild-moderate inflammation uv...
Authors: Athimalaipet V. Ramanan, Andrew D. Dick, Ashley P. Jones, Catherine Guly, Ben Hardwick, Helen Hickey, Richard Lee, Andrew McKay and Michael W. Beresford
An important source of knowledge, beliefs, and attitudes about illness is the mass media. Research has established the often negative and emotive language utilised by journalists to report on physical and ment...
Authors: Andrew Mark Bassett, Savia de Souza, Ruth Williams and Heidi Lempp
Multiple targeted immunomodulators (TIMs) for psoriatic arthritis (PsA) treatment are available, but limited studies have directly compared these agents. This study indirectly compared the efficacy of TNF-α, i...
Authors: Vibeke Strand, M. Elaine Husni, Keith A. Betts, Yan Song, Rakesh Singh, Jenny Griffith, Marci Beppu, Jing Zhao and Arijit Ganguli
Total hip (THA) and total knee arthroplasty (TKA) are widely used, successful procedures for symptomatic end stage arthritis of the hips or knees, but patients with rheumatoid arthritis (RA), systemic lupus er...
Early and intensive targeted treatment with disease modifying anti-rheumatic drugs (DMARDs) has been shown to lead to substantial reductions in disease activity and radiograph damage in patients with early rhe...
Authors: Laura M. M. Steunebrink, Letty G. A. Versteeg, Harald E. Vonkeman, Peter M. ten Klooster, Monique Hoekstra and Mart A. F. J. van de Laar
To examine the frequency of possible giant cell arteritis (GCA) symptoms (including headache, temporal/scalp tenderness, jaw claudication and visual symptoms) in newly diagnosed polymyalgia rheumatica (PMR) pa...
Authors: William Masson, Sara Muller, Rebecca Whittle, James Prior, Toby Helliwell, Christian Mallen and Samantha L. Hider
The idiopathic inflammatory myopathies (IIM, myositis) are a heterogeneous group of chronic autoimmune disorders causing considerable physical and mental health impact. There is a lack of formalised guidance d...
Authors: James B. Lilleker, Patrick Gordon, Janine A. Lamb, Heidi Lempp, Robert G. Cooper, Mark E. Roberts, Paula Jordan and Hector Chinoy
This editorial accompanies the launch of BMC Rheumatology, a new open access, peer-reviewed journal within the BMC Series portfolio, which considers studies on all aspects of rheumatological diseases. The Journal...
Authors: James Mockridge, Alessia Alunno, Susan Goodman and Edward Roddy
To determine the prevalence of depression among Japanese people with rheumatoid arthritis (RA) and explore the relationships between depression and an array of variables.
Authors: Rosarin Sruamsiri, Yuko Kaneko and Jörg Mahlich
Being physically active is an essential component of successful self-management for people with inflammatory arthritis; however, the vast majority of patients are inactive. This study aims to determine whether...
Authors: Linda C. Li, Lynne M. Feehan, Chris Shaw, Hui Xie, Eric C. Sayre, Antonio Aviña-Zubeita, Navi Grewal, Anne F. Townsend, Diane Gromala, Greg Noonan and Catherine L. Backman
