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  1. The pathophysiology of osteoarthritis (OA) involves wear and tear, and a state of low-grade inflammation. Tissue repair responses include transforming growth factor beta (TGFβ)-induced myofibroblast production...

    Authors: Tue W. Kragstrup, Dong H. Sohn, Christin M. Lepus, Kazuhiro Onuma, Qian Wang, William H. Robinson and Jeremy Sokolove

    Citation: BMC Rheumatology 2019 3:46

    Content type: Research article

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  2. Patients with psoriatic arthritis (PsA) have increased risk of adverse events, including serious infections (SI), compared with psoriasis patients.

    Authors: Christopher T. Ritchlin, Mona Stahle, Yves Poulin, Jerry Bagel, Soumya D. Chakravarty, Shelly Kafka, Bhaskar Srivastava, Wayne Langholff and Alice B. Gottlieb

    Citation: BMC Rheumatology 2019 3:52

    Content type: Research article

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  3. RA flares are common and disabling. They are described in terms of worsening inflammation but pain and inflammation are often discordant. To inform treatment decisions, we investigated whether inflammatory and...

    Authors: Daniel F. McWilliams, Shimin Rahman, Richard J. E. James, Eamonn Ferguson, Patrick D. W. Kiely, Adam Young and David A. Walsh

    Citation: BMC Rheumatology 2019 3:49

    Content type: Research article

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  4. There is an ongoing discussion about incorporating additional risk factors to established WHO fracture risk assessment tool (FRAX) to improve the prediction accuracy in clinical subgroups. We aimed to reach an...

    Authors: Nicolas S. Bodmer, Hans Jörg Häuselmann, Diana Frey, Daniel Aeberli and Lucas M. Bachmann

    Citation: BMC Rheumatology 2019 3:50

    Content type: Research article

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  5. The prevalence of mood disturbances such as anxiety and depression is greater in rheumatoid arthritis (RA) patients than in the general population. Given this association, the primary aim of this study was to ...

    Authors: Steve Peterson, James Piercy, Stuart Blackburn, Emma Sullivan, Chetan S. Karyekar and Nan Li

    Citation: BMC Rheumatology 2019 3:43

    Content type: Research article

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  6. Work and workplace factors are important in fibromyalgia management. We investigated factors associated with sick leave in professionally active women living with fibromyalgia.

    Authors: F. Laroche, D. Azoulay, A. P. Trouvin, J. Coste and S. Perrot

    Citation: BMC Rheumatology 2019 3:44

    Content type: Research article

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  7. The idiopathic inflammatory myopathies (IIMs) are a group of rare conditions characterised by muscle inflammation (myositis). Accurate disease activity assessment is vital in both clinical and research setting...

    Authors: Alexander Oldroyd, Max A. Little, William Dixon and Hector Chinoy

    Citation: BMC Rheumatology 2019 3:41

    Content type: Research article

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  8. The objective of this study was to develop an assessment tool, ReproKnow, to evaluate the reproductive health knowledge of women with a wide range of rheumatic diseases.

    Authors: Mehret Birru Talabi, Megan E. B. Clowse, Susan J. Blalock, Galen Switzer, Lan Yu, Alaina Chodoff and Sonya Borrero

    Citation: BMC Rheumatology 2019 3:40

    Content type: Research article

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  9. There has been much variation between epidemiological studies that report the prevalence of ankylosing spondylitis (AS). This study aimed to analyze the diagnostic prevalence rates and treatment patterns of ma...

    Authors: Jessica Walsh, Theresa Hunter, Krista Schroeder, David Sandoval and Rebecca Bolce

    Citation: BMC Rheumatology 2019 3:39

    Content type: Research article

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  10. Group B Streptococcus (GBS) emerged as the frequent pathogen for septic arthritis. There was no study comparing risks, clinical presentations and outcomes between GBS septic arthritis and other bacterial septi...

    Authors: Rungkan Ruksasakul, Pongthorn Narongroeknawin, Paijit Assavatanabodee and Sumapa Chaiamnuay

    Citation: BMC Rheumatology 2019 3:38

    Content type: Research article

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  11. Rheumatoid arthritis (RA) is associated with a 5 to 10 years reduction in life expectancy due to premature atherosclerosis. This reduction is the consequence of traditional cardiovascular risk factors (TCRF) a...

    Authors: Christophe Mulumba, Pierrot Lebughe, Jean-Marie Mbuyi-Muamba, Jean-Robert Makulo, François Lepira, Jean Mukaya, Rene Westhovens, Patrick Verschueren and Jean-Jacques Malemba

    Citation: BMC Rheumatology 2019 3:37

    Content type: Research article

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  12. Patient-reported outcomes (PROs) aid in rheumatoid arthritis (RA) management, but it is not well understood which measures would be most relevant to the rheumatologists for making treatment decisions.

    Authors: Aprajita Jagpal, Ronan O’Beirne, Melanie S. Morris, Bernadette Johnson, James Willig, Huifeng Yun, Andrea L. Cherrington, Liana Fraenkel, Jeffrey R. Curtis, Monika M. Safford and Iris Navarro-Millán

    Citation: BMC Rheumatology 2019 3:36

    Content type: Research article

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  13. To undertake a retrospective review of patients with SLE who had received Rituximab in order to determine the rates and associated patient characteristics of clinically significant adverse infusion reactions.

    Authors: Ashleigh Hennessey, Joanna Lukawska, Geraldine Cambridge, David Isenberg and Maria Leandro

    Citation: BMC Rheumatology 2019 3:32

    Content type: Research article

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  14. Hypogammaglobulinemia is a complication of B-cell targeting therapies (BCTT), used in vasculitis, rheumatoid arthritis and systemic lupus erythematosus (SLE). Since autoimmune diseases are associated with unde...

    Authors: M. J. Cuadrado, I. Calatayud, M. Urquizu-Padilla, S. Wijetilleka, S. Kiani-Alikhan and M. Y. Karim

    Citation: BMC Rheumatology 2019 3:30

    Content type: Research article

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  15. An error occurred during the publication of a number of articles in BMC Rheumatology. Several articles were published in volume 3 with a duplicate citation number.

    Authors:

    Citation: BMC Rheumatology 2019 3:35

    Content type: Publisher Correction

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    The original article was published in BMC Rheumatology 2019 3:21

    The original article was published in BMC Rheumatology 2019 3:20

    The original article was published in BMC Rheumatology 2019 3:22

    The original article was published in BMC Rheumatology 2019 3:24

    The original article was published in BMC Rheumatology 2019 3:23

  16. Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily affects joints with some extraarticular involvement. If inappropriately treated, it usually results in persistent joint pain, i...

    Authors: Wanruchada Katchamart, Pongthorn Narongroeknawin, Wanwisa Chanapai and Phakhamon Thaweeratthakul

    Citation: BMC Rheumatology 2019 3:34

    Content type: Research article

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  17. The objective of this study was to explore the associations between ultrasonographic and radiographic joint scores and levels of arterial CVD risk markers in patients with osteoarthritis (OA). Secondly, to com...

    Authors: S. A. Provan, S. Rollefstad, E. Ikdahl, A. Mathiessen, I. J. Berg, I. Eeg, I. B. Wilkinson, C. M. McEniery, T. K. Kvien, H. B. Hammer, N. Østerås, I. K. Haugen and A. G. Semb

    Citation: BMC Rheumatology 2019 3:33

    Content type: Research article

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  18. Administrative database research is widely applied in the field of epidemiology. However, the results of the studies depend on the type of database used and the algorithms applied for case ascertainment. The o...

    Authors: Kati Otsa, Sandra Talli, Pille Harding, Eevi Parsik, Marge Esko, Anti Teepere and Marika Tammaru

    Citation: BMC Rheumatology 2019 3:26

    Content type: Research article

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  19. Methods of gout flare reporting in research settings are inconsistent and poorly defined. The aim of this study was to describe patterns of gout flare and assess the concurrent validity of different methods of...

    Authors: Novell Teoh, Gregory D. Gamble, Anne Horne, William J. Taylor, Kate Palmano and Nicola Dalbeth

    Citation: BMC Rheumatology 2019 3:27

    Content type: Research article

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  20. Heterogeneity in assessments of rheumatoid arthritis (RA) disease remission, based on physician judgment and patient self-reports versus standardized measures, have previously been reported. This study explore...

    Authors: Wenhui Wei, Emma Sullivan, Stuart Blackburn, Chieh-I Chen, James Piercy and Jeffrey R. Curtis

    Citation: BMC Rheumatology 2019 3:25

    Content type: Research article

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  21. Previous studies of prognosis for women with Fibromyalgia (FM) or chronic widespread pain (CWP) show contradictory results. However, some women appear to improve in pain and other core symptoms over time. Ther...

    Authors: Anna Bergenheim, Sofia Juhlin, Lena Nordeman, Monica Joelsson and Kaisa Mannerkorpi

    Citation: BMC Rheumatology 2019 3:21

    Content type: Research article

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    The Publisher Correction to this article has been published in BMC Rheumatology 2019 3:35

  22. The role of self-care behaviors in promoting physical function, pain management, health status and quality of life among patients with Rheumatoid Arthritis (RA) is well documented. However, there is no valid a...

    Authors: Haidar Nadrian, Yasna Hosseini Niaz, Zahra Basiri and Ahmad Tahamoli Roudsari

    Citation: BMC Rheumatology 2019 3:20

    Content type: Research article

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    The Publisher Correction to this article has been published in BMC Rheumatology 2019 3:35

  23. Withdrawal of disease-modifying anti-rheumatic drugs (DMARDs) once disease remission is achieved is endorsed by current international rheumatoid arthritis (RA) management guidelines. However, very little data ...

    Authors: Kenneth F. Baker, John D. Isaacs and Ben Thompson

    Citation: BMC Rheumatology 2019 3:24

    Content type: Research article

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    The Publisher Correction to this article has been published in BMC Rheumatology 2019 3:35

  24. The aim of this study was to identify predictors of prolonged disease control after discontinuation of tumor necrosis factor inhibitor (TNFi) treatment in patients with rheumatoid arthritis (RA).

    Authors: Marjan Ghiti Moghadam, Femke B. G. Lamers-Karnebeek, Harald E. Vonkeman, Peter M. ten Klooster, Janneke Tekstra, Barbara van Schaeybroeck, Ruth Klaasen, Marieke van Onna, Hein J. Bernelot Moens, Henk Visser, Annemarie M. Schilder, Marc R. Kok, Robert B. M. Landewé, Piet L. C. M. van Riel, Mart A. F. J. van de Laar and Tim L. Jansen

    Citation: BMC Rheumatology 2019 3:22

    Content type: Research article

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    The Publisher Correction to this article has been published in BMC Rheumatology 2019 3:35

  25. A fatty corner lesion (FCL) is a well-demarcated fat infiltration in the corner of a vertebral body on T1 magnetic resonance imaging (MRI) sequence. It has been reported to be useful in the diagnosis of axial ...

    Authors: Ho Yin Chung, Rachel Sze Wan Yiu, Shirley Chiu Wai Chan, Kam Ho Lee and Chak Sing Lau

    Citation: BMC Rheumatology 2019 3:17

    Content type: Research article

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  26. Good communication is central to a high-quality consultation process. We assessed the quality of referral information from primary care physicians (PCPs) to rheumatologists and the quality and timeliness of co...

    Authors: Jenna Wong, Karen Tu, Sasha Bernatsky, Liisa Jaakkimainen, J. Carter Thorne, Vandana Ahluwalia, J. Michael Paterson and Jessica Widdifield

    Citation: BMC Rheumatology 2019 3:23

    Content type: Research article

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    The Publisher Correction to this article has been published in BMC Rheumatology 2019 3:35

  27. Around 1 in 8 patients with axial spondyloarthritis (axSpA) also meet criteria for fibromyalgia and such patients have considerable unmet need. Identifying effective therapy is important but to what extent fib...

    Authors: Gary J. Macfarlane, Ejaz Pathan, Stefan Siebert, Jonathan Packham, Karl Gaffney, Ernest Choy, Raj Sengupta, Fabiola Atzeni, Kathryn R. Martin, Gareth T. Jones and Linda E. Dean

    Citation: BMC Rheumatology 2019 3:19

    Content type: Research article

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  28. With improved therapies and management, more women with inflammatory arthritides (IA) are considering pregnancy. Our objective was to survey rheumatologists across Canada about their IA management in pregnancy...

    Authors: Mary A. De Vera, Corisande Baldwin, Nicole W. Tsao, Alyssa Howren, Glen S. Hazlewood, Nevena Rebić and Stephanie Ensworth

    Citation: BMC Rheumatology 2019 3:18

    Content type: Research article

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  29. Adjusting medication of patients with rheumatoid arthritis (RA) until predefined disease activity targets are met, i.e. Treat-to-Target (T2T), is the currently recommended treatment approach. However, not much...

    Authors: Celine J. van de Laar, Martijn A. H. Oude Voshaar and Harald E. Vonkeman

    Citation: BMC Rheumatology 2019 3:16

    Content type: Research article

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  30. The details of two rheumatoid arthritis (RA) patients with systemic sclerosis (SSc) who were administered tocilizumab, an anti-interleukin-6 receptor antibody, are reported, along with a review of the literature.

    Authors: Hiroki Wakabayashi, Hitoshi Kino, Makoto Kondo, Keiichi Yamanaka, Masahiro Hasegawa and Akihiro Sudo

    Citation: BMC Rheumatology 2019 3:15

    Content type: Case report

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  31. The pathobiology of rheumatoid arthritis (RA) is similar to that of periodontitis in that proinflammatory cytokines play an important pathologic role. There is evidence to suggest that inhibitors of tumor necr...

    Authors: Tetsuo Kobayashi, Satoshi Ito, Akira Murasawa, Hajime Ishikawa and Hiromasa Yoshie

    Citation: BMC Rheumatology 2019 3:13

    Content type: Case report

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  32. The TITRATE trial seeks to test whether intensive management is valuable in achieving disease remission in moderately active rheumatoid arthritis. Intensive management is a complex intervention consisting of: ...

    Authors: Louise Prothero, Jackie Sturt, Savia de Souza and Heidi Lempp

    Citation: BMC Rheumatology 2019 3:12

    Content type: Research article

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  33. Uncontrolled gout can cause significant joint and organ damage and has been associated with impairments in quality of life and high economic cost. Gout has also been associated with other comorbid diseases, su...

    Authors: Dena H. Jaffe, Alyssa B. Klein, Arriel Benis, Natalia M. Flores, Hagit Gabay, Robert Morlock, Dana Y. Teltsch, Jonathan Chapnick, Yair Molad, Shmuel M. Giveon, Becca Feldman and Maya Leventer-Roberts

    Citation: BMC Rheumatology 2019 3:11

    Content type: Research article

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  34. Inhibitors of tumor necrosis factor alpha (TNF-α) are current mainstay of therapies for rheumatoid arthritis (RA). The decision when to withdraw TNF-α inhibitors after achieving remission and the incidence of ...

    Authors: Arduino A. Mangoni, Fahdah Al Okaily, Hani Almoallim, Seham Al Rashidi, Reem Hamdy A. Mohammed and Amal Barbary

    Citation: BMC Rheumatology 2019 3:10

    Content type: Research article

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  35. Anti-neutrophil cytoplasmic antibodies associated vasculitides (AAV) are characterized by autoimmune small vessel inflammation. Eosinophils are multifunctional cells with both pro-inflammatory and immunoregula...

    Authors: Thomas Hellmark, Sophie Ohlsson, Åsa Pettersson, Markus Hansson and Åsa C. M. Johansson

    Citation: BMC Rheumatology 2019 3:9

    Content type: Research article

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  36. Signs and symptoms establish the diagnosis of adult onset Still’s disease (AOSD) as well as of systemic onset juvenile idiopathic arthritis (sJIA). The published data regarding the importance of IL-18 as a mar...

    Authors: Holger Kudela, Susanne Drynda, Anke Lux, Gerd Horneff and Joern Kekow

    Citation: BMC Rheumatology 2019 3:4

    Content type: Research article

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  37. The emphasis on treating rheumatoid arthritis (RA) intensively reduces disease activity but its impact in routine care is uncertain. We evaluated temporal changes in disease activities and outcomes in a 10-yea...

    Authors: Nicola J. Gullick, Fowzia Ibrahim, Ian C. Scott, Alexandra Vincent, Andrew P. Cope, Toby Garrood, Gabriel S. Panayi, David L. Scott and Bruce W. Kirkham

    Citation: BMC Rheumatology 2019 3:6

    Content type: Research article

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  38. Hemophagocytic lymphohistiocytosis (HLH) is a severe clinical entity associated with high mortality in the adult population. HLH has been associated with infections, malignancy and autoimmune conditions such a...

    Authors: Christina S. Thornton, Parham Minoo, Michelle Schneider and Aurore Fifi-Mah

    Citation: BMC Rheumatology 2019 3:7

    Content type: Case report

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  39. Rheumatoid arthritis is an autoimmune disease that causes joint inflammation. It affects around 400,000 people in the UK and 1 million adults in the USA. Given the appropriate treatment, many can have relative...

    Authors: Fran Toye, Kate Seers and Karen Louise Barker

    Citation: BMC Rheumatology 2019 3:5

    Content type: Research article

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  40. Biomarkers of rheumatoid arthritis (RA) disease activity typically measure inflammation or autoimmunity (e.g. CRP, RF). C1M and C3M, metabolites of type I and III collagen, are markers reflecting tissue metabo...

    Authors: Anne C. Bay-Jensen, Adam Platt, Martin A. Jenkins, Michael E. Weinblatt, Inger Byrjalsen, Kishwar Musa, Mark C. Genovese and Morten A. Karsdal

    Citation: BMC Rheumatology 2019 3:3

    Content type: Research article

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  41. Fibromyalgia is characterized by chronic generalized pain, fatigue, sleep disorders and other symptoms. Physical exercise is recommended as the first choice of non-pharmacological therapy. Thus, the aim of thi...

    Authors: Katherinne Ferro Moura Franco, Yuri Rafael dos Santos Franco, Evany Maira Espírito Santo Salvador, Bruna Cristina Brajon do Nascimento, Gisela Cristiane Miyamoto and Cristina Maria Nunes Cabral

    Citation: BMC Rheumatology 2019 3:2

    Content type: Study protocol

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  42. Tumour necrosis factor inhibitor (TNFi) therapy has been available for rheumatoid arthritis (RA) patients for several decades but data on the long-term risk of malignancy associated with its use is limited. Ou...

    Authors: Margaret P. Staples, Lyn March, Catherine Hill, Marissa Lassere and Rachelle Buchbinder

    Citation: BMC Rheumatology 2019 3:1

    Content type: Research article

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  43. Fibromyalgia (FM) is a complex, centralized pain condition that is often difficult to diagnose and treat. FM is considered to have a genetic background due to its familial aggregation and due to findings from ...

    Authors: Chee Lee, Ginevra Liptan, Svetlana Kantorovich, Maneesh Sharma and Ashley Brenton

    Citation: BMC Rheumatology 2018 2:38

    Content type: Research article

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