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Table 3 Comparison of genotypes of PTPN22 gene R620W functional variant between SLE patients group and controls stratified according to gender

From: High prevalence of protein tyrosine phosphatase non-receptor N22 gene functional variant R620W in systemic lupus erythematosus patients from Kuwait: implications for disease susceptibility

Genotype/Gender

SLE patients

N (%)

Control

N (%)

P-valuea

CC

(N = 76)

(N = 177)

< 0.001*

Female

70 (92.1)

115 (65)

Male

6 (7.9)

62 (35)

CT

(N = 21)

(N = 32)

< 0.001*

Female

21 (100)

19 (59.4)

Male

0 (0)

13 (40.6)

TT

(N = 21)

(N = 2)

0.25

Female

19 (90.5)

1 (50)

Male

2 (9.5)

1 (50)

  1. aChi-square test of the full cohort
  2. *P-value were considered significant when < 0.05
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BMC Rheumatology

ISSN: 2520-1026

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