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Table 3 Comparison of genotypes of PTPN22 gene R620W functional variant between SLE patients group and controls stratified according to gender

From: High prevalence of protein tyrosine phosphatase non-receptor N22 gene functional variant R620W in systemic lupus erythematosus patients from Kuwait: implications for disease susceptibility

Genotype/Gender SLE patients
N (%)
Control
N (%)
P-valuea
CC (N = 76) (N = 177) < 0.001*
Female 70 (92.1) 115 (65)
Male 6 (7.9) 62 (35)
CT (N = 21) (N = 32) < 0.001*
Female 21 (100) 19 (59.4)
Male 0 (0) 13 (40.6)
TT (N = 21) (N = 2) 0.25
Female 19 (90.5) 1 (50)
Male 2 (9.5) 1 (50)
  1. aChi-square test of the full cohort
  2. *P-value were considered significant when < 0.05