Fig. 3

Venn diagrams showing the numbers of protein spots with significantly different intensities between the HL group and each disease group. (a) (i) Numbers of protein spots with significantly different intensities between the wRA and HL groups and between the OA and HL groups (p < 0.05). Up and down arrows indicate the spots whose intensity was higher and lower, respectively, in the disease groups than that in HL group. (ii) IDs of protein spots with an intensity ≥ ±1.3-fold different in the diagram (i). IDs of protein spots with a significantly different intensity between the wRA and OA groups are boxed. Up and down arrows indicate the spots whose intensity was higher and lower, respectively, compared to the intensity of the identical spots in the HL group. (b) (i) Numbers of protein spots with significantly different intensities between the aRA and HL groups, between the iRA and HL groups, and between the OA and HL groups (p < 0.05). Up and down arrows indicate the spots whose intensity was higher and lower, respectively, in the disease groups than that in HL group. The spots with “*” showed a higher intensity in the aRA group and a lower intensity in the iRA and OA groups than in the HL group. (ii) IDs of protein spots with an intensity ≥ ±1.3-fold different in the diagram (i). IDs of protein spots with a significantly different intensity between the aRA and OA groups and between the aRA and iRA groups are boxed. Up and down arrows indicate the spots whose intensity was higher and lower, respectively, compared to the intensity of the identical spots in the HL group