Skip to main content

Table 1 Patient demographics and clinical characteristics

From: The prevalence and types of discordance between physician perception and objective data from standardized measures of rheumatoid arthritis disease activity in real-world clinical practice in the US

Characteristic Concordant Discordant
Overall
(n = 531)
Not in remission
(n = 231)
In remission
(n = 127)
Rheumatologist negatively discordanta
(n = 137)
Rheumatologist positively discordant
(n = 36)
Age, in years, mean (SD) 56.4 (15.5) 56.7 (15.5) 53.1 (16.6) 59.0 (14.2)** 56.4 (15.2)
Female gender, n (%) 397 (74.8) 177 (76.6) 89 (70.1) 101 (73.7) 30 (83.3)
BMI, mean (SD) 28.0 (6.3) 28.3 (6.9) 27.3 (5.9) 27.7 (5.3) 29.0 (6.8)
White, n (%) 363 (68.4) 152 (65.8) 87 (68.5) 94 (68.8) 30 (83.3)
Time since diagnosis of RA, years (SD) 7.6 (8.1) 7.2 (8.6) 5.9 (6.1) 9.8 (8.8)** 7.7 (7.3)
Current assessment of level of pain, mean (SD)b 2.8 (2.0) 4.2 (2.2) 1.4 (0.9) 1.9 (1.0) 2.4 (1.2)
Current DAS28(3) score, mean (SD) 3.6 (1.5) 1.9 (0.6) 4.8 (1.2) 1.9 (0.5) 3.7 (0.8)
Marginal bone erosion present, n (%) 164 (30.9) 89 (38.5) 20 (15.7) 48 (35.0)** 7 (19.4)
Synovium inflammation present, n (%) 185 (34.8) 132 (57.1) 9 (7.1) 32 (23.4)** 12 (33.3)
Osteoporosis present, n (%) 127 (23.9) 68 (29.4) 19 (15.0) 37 (27.0)* 3 (8.3)
No RA-related bone/joint inflammation or damage present, n (%) 179 (33.7) 44 (19.0) 75 (59.1) 47 (34.3)** 13 (36.1)
On bDMARD, n (%) 283 (53.3) 120 (51.9) 58 (45.7) 83 (60.6)* 22 (61.1)
Patient managed by physician based in hospital or mixed (hospital + office) practice, n (%) 332 (62.5) 138 (59.7) 92 (72.4) 80 (58.4)* 22 (61.1)
Rheumatologist has an agreed T2T measure for patient, n (%) 213 (40.1) 81 (35.1) 68 (53.5) 54 (39.4)* 10 (27.8)
Time managed by current rheumatologist, years (SD) 4.5 (4.6) 4.0 (4.9) 4.4 (4.1) 5.3 (4.0)** 5.1 (5.8)
  1. bDMARD Biologic disease modifying antirheumatic drug, BMI Body mass index, DAS28(3) Disease activity score in 28 joints 3, RA Rheumatoid arthritis, SD Standard deviation, T2T Treat-to-target
  2. *P < 0.05
  3. **P < 0.005
  4. aBivariate analysis was performed between Concordant – in remission and Rheumatologist – negatively discordant cohort. Rheumatologist – negatively discordant: patient in remission as per rheumatologist evaluation, but not in remission by standardized measure (i.e. rheumatologist underestimating disease activity versus standardized measure). Rheumatologist – positively discordant: patient not in remission as per rheumatologist evaluation, but in remission by standardized measure. (i.e. rheumatologist overestimating disease activity versus standardized measure)
  5. bLow [1–3], Medium/high [4–10]