Table 1 Patient demographics and clinical characteristics
Characteristic | Concordant | Discordant | |||
|---|---|---|---|---|---|
Overall (n = 531) | Not in remission (n = 231) | In remission (n = 127) | Rheumatologist negatively discordanta (n = 137) | Rheumatologist positively discordant (n = 36) | |
Age, in years, mean (SD) | 56.4 (15.5) | 56.7 (15.5) | 53.1 (16.6) | 59.0 (14.2)** | 56.4 (15.2) |
Female gender, n (%) | 397 (74.8) | 177 (76.6) | 89 (70.1) | 101 (73.7) | 30 (83.3) |
BMI, mean (SD) | 28.0 (6.3) | 28.3 (6.9) | 27.3 (5.9) | 27.7 (5.3) | 29.0 (6.8) |
White, n (%) | 363 (68.4) | 152 (65.8) | 87 (68.5) | 94 (68.8) | 30 (83.3) |
Time since diagnosis of RA, years (SD) | 7.6 (8.1) | 7.2 (8.6) | 5.9 (6.1) | 9.8 (8.8)** | 7.7 (7.3) |
Current assessment of level of pain, mean (SD)b | 2.8 (2.0) | 4.2 (2.2) | 1.4 (0.9) | 1.9 (1.0) | 2.4 (1.2) |
Current DAS28(3) score, mean (SD) | 3.6 (1.5) | 1.9 (0.6) | 4.8 (1.2) | 1.9 (0.5) | 3.7 (0.8) |
Marginal bone erosion present, n (%) | 164 (30.9) | 89 (38.5) | 20 (15.7) | 48 (35.0)** | 7 (19.4) |
Synovium inflammation present, n (%) | 185 (34.8) | 132 (57.1) | 9 (7.1) | 32 (23.4)** | 12 (33.3) |
Osteoporosis present, n (%) | 127 (23.9) | 68 (29.4) | 19 (15.0) | 37 (27.0)* | 3 (8.3) |
No RA-related bone/joint inflammation or damage present, n (%) | 179 (33.7) | 44 (19.0) | 75 (59.1) | 47 (34.3)** | 13 (36.1) |
On bDMARD, n (%) | 283 (53.3) | 120 (51.9) | 58 (45.7) | 83 (60.6)* | 22 (61.1) |
Patient managed by physician based in hospital or mixed (hospital + office) practice, n (%) | 332 (62.5) | 138 (59.7) | 92 (72.4) | 80 (58.4)* | 22 (61.1) |
Rheumatologist has an agreed T2T measure for patient, n (%) | 213 (40.1) | 81 (35.1) | 68 (53.5) | 54 (39.4)* | 10 (27.8) |
Time managed by current rheumatologist, years (SD) | 4.5 (4.6) | 4.0 (4.9) | 4.4 (4.1) | 5.3 (4.0)** | 5.1 (5.8) |