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Table 1 Proteins upregulated in the conditioned media of IL-17A [100 ng/ml] samples when compared to untreated (adjusted p-value < 0.05)

From: Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study

Accession​

Description​

Gene

ROTS-statistic​

P-value​

FDR​

Q8SQB1​

C-C motif chemokine 20

CCL20

− 75.2501

0.0016

0​

Q8SQ28​

Serum amyloid A protein

SAA3

− 75.1999

0.0032

0​

G3X7D2​

Chitinase-3-like protein 1

CHI3L1

− 70.1621

0.0048

0​

P80221​

C-X-C motif chemokine 6

CXCL6

− 69.4439

0.0064

0​

F1MF86​

Latent-transforming growth factor beta-binding protein 2

LTBP2

− 68.0478

0.0080

0​

F1MRZ2​

A disintegrin and metalloproteinase with thrombospondin motifs 5

ADAMTS5

− 63.8272

0.0096

0​

F1MTX6​

Matrix metalloproteinase

MMP3

− 61.1325

0.0112

0​

P81187​

Complement factor B

CFB

− 60.5126

0.0128

0​

F1MXR3​

ADAMTS like 4

ADAMTSL4

− 59.5466

0.0144

0​

Q5GN72​

Alpha-1-acid glycoprotein

AGP

− 56.2470

0.0160

0​

F1MD77​

Laminin subunit gamma 1

LAMC1

−54.4637

0.0176

0​

E1BKX7​

Filamin B

FLNB

−54.1942

0.0191

0​

P33072​

Protein-lysine 6-oxidase

LOX

−50.8668

0.0207

0​

Q58CQ9​

Pantetheinase

VNN1

−50.7081

0.0223

0​

P26892​

Interleukin-6

IL6

−50.1170

0.0239

0​

Q6B411​

Lysozyme C, milk isozyme

LYZ

−45.5667

0.0255

0​