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Table 4 Relationships between meningitis/encephalitis and chondritis in RP patients based on a review of the literaturea

From: Elucidation of predictors of disease progression in patients with relapsing polychondritis at the onset: potential impact on patient monitoring

  Mean age at onset (y) Male to female ratio Time intervalb (months) Follow-upc (months) Onset Last follow-up
AO RO MO AL RL BL
All patients (n = 50) 56 ± 1.5d 3.2:1 NAe 13 ± 2.0 34 4 22 41 0 9
Patients presented with meningitis/encephalitis and developed chondritis later (n = 14) 57 ± 3.1 3.7:1 6.2 ± 1.6 8.5 ± 2.1 0 0 3 13 0 1
Patients presented with chondritis and developed meningitis/encephalitis later (n = 17) 58 ± 2.3 7.5:1 12 ± 4.3 18 ± 4.3 16 1 7 14 0 3
Patients presented with both meningitis/encephalitis and chondritis (n = 19) 55 ± 2.4 1.7:1 NA 11 ± 3.5 18 3 12 14 0 5
  1. aA review of the literature was conducted on RP meningitis/encephalitis using PubMed [18, 22,23,24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42]
  2. bTime interval (months) between the onset of meningitis/encephalitis and that of chondritis
  3. cFollow-up duration of patients (months)
  4. dAge, time interval, and follow-up duration were expressed as mean ± standard error of the mean
  5. eNA, Not applicable