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Fig. 3 | BMC Rheumatology

Fig. 3

From: Characterization of the mechanism of action of lanraplenib, a novel spleen tyrosine kinase inhibitor, in models of lupus nephritis

Fig. 3

Kidney morphology is improved by lanraplenib treatment in NZB/W mice. a Average glomerulus diameter of kidney sections. Each point represents an individual mouse at the time of sacrifice. b Summed histology score of kidney sections. c Representative glomerular IgG staining for each group. Green: anti-IgG staining; red: DAPI. Scale bar represents 100 μm. d Summary of glomerular IgG staining. Scoring criteria are specified in Fig. S3. Mean ± SD are indicated for each treatment group. Statistics were calculated comparing the vehicle control group to each other group using either an ANOVA or Kruskal-Wallis test. *Indicates P < 0.05. ** Indicates P < 0.005. *** Indicates P < 0.0005

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BMC Rheumatology

ISSN: 2520-1026

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