Skip to main content

Table 1 Classification criteria for mixed connective tissue disease

From: Capillaroscopy as a diagnostic tool in the diagnosis of mixed connective tissue disease (MCTD): a case report

A. Common symptoms
 1. Raynaud’s phenomenon
 2. “Swollen”/“puffy” fingers or hands
B. Anti-U1snRNP antibodies
C. Miscellaneous
1. Lupus Manifestations
  a. Polyarthritis
  b. Adenopathies
  c. Malar erythema
  d. Serositis (pleuritis or pericarditis)
  e. Cytopenia (leukopenia or thrombocytopenia)
2. Sclerodermiform manifestations
  a. Sclerodactyly
  b. Pulmonary fibrosis, restriction or decrease of diffusion < 70%
  c. Hypomotility or oesophageal dilation
3. Myositis
  a. Muscular weakness
  b. Muscle enzymes (CK) increase
  c. Myopathic pattern on EMG
  1. CK creatine kinase, EMG electromyography, snRNP small nuclear ribonucleoprotein
  2. At least 1 of the 2 common symptoms is required, plus positive anti-U1snRNP antibodies, plus one or more of the miscellaneous symptoms in at least 2 of the 3 categories. Kasukawa et al. [17]