Table 1 Baseline disease characteristic for bDMARD- naïve and TNFi-experienced patients in COAST-V and COAST-W
COAST-V: bDMARD-naïve (N = 329) | COAST-W: TNFi-experienced (N = 281) | |||
|---|---|---|---|---|
Mean (range) | SD | Mean (range) | SD | |
Age, years | 41.6 (19–78) | 11.7 | 46.3 (18–76) | 12.3 |
Duration of disease since diagnosis, years | 7.7 (0–43.9) | 8.4 | 11.4 (0.3–43.8) | 9.2 |
ASAS treatment response domains | ||||
PtGA | 7.1 (1–10) | 1.6 | 7.9 (0–10) | 1.6 |
Spinal pain (BASDAI Q2) | 7.3 (3–10) | 1.5 | 8.2 (4–10) | 1.3 |
Function (BASFI) | 6.2 (0.8–10) | 1.9 | 7.2 (0.7–10) | 1.7 |
Stiffness (BASDAI Q5/Q6) | 6.7 (1–10) | 1.7 | 7.2 (2–10) | 1.7 |
Other outcomes | ||||
Fatigue (NRS) | 6.8 (0–10) | 1.7 | 7.3 (0–10) | 1.7 |
Fatigue (BASDAI Q1) | 7.1 (2–10) | 1.6 | 7.6 (3–10) | 1.4 |
Spinal pain at night | 7.1 (2–10) | 1.6 | 7.7 (0–10) | 1.7 |
Sleep (JSEQ) | 8.2 (0–20) | 5.2 | 10.2 (0–20) | 5.6 |
BASDAI | 6.7 (2.8–10) | 1.4 | 7.4 (3.4–10) | 1.3 |