Table 1 Summary of baseline demographics, disease and clinical characteristics of the AGREE study patients (N = 509)
|  | ABA + MTX (N = 256) | MTX (N = 253) | Total (N = 509) | |||
|---|---|---|---|---|---|---|
n | Value | n | Value | n | Value | |
Age in years, mean (SD) | 256 | 50.1 (12.4) | 253 | 49.7 (13.0) | 509 | 49.9 (12.7) |
Gender, n (%) female | 256 | 196 (76.6) | 253 | 199 (78.7) | 509 | 395 (77.6) |
Race, n (%) White | 256 | 202 (78.9) | 253 | 219 (86.6) | 509 | 421 (82.7) |
Disease duration in months, mean (SD) | 256 | 6.2 (7.5) | 253 | 6.7 (7.1) | 509 | 6.5 (7.3) |
Tender joints, mean (SD)* | 256 | 31.3 (14.8) | 253 | 30.8 (14.0) | 509 | 31.0 (14.4) |
Swollen joints, mean (SD)* | 256 | 22.9 (11.3) | 253 | 21.9 (10.1) | 509 | 22.4 (10.8) |
DAS28-CRP, mean (SD) | 256 | 6.3 (1.0) | 252 | 6.2 (1.0) | 508 | 6.3 (1.0) |
HAQ DI, mean (SD) | 254 | 1.7 (0.7) | 251 | 1.7 (0.7) | 505 | 1.7 (0.7) |
ACPA-positive, n (%) | 256 | 236 (92.2) | 253 | 217 (85.8) | 509 | 453 (89.0) |
RF-positive, n (%) | 256 | 246 (96.1) | 253 | 245 (96.8) | 509 | 491 (96.5) |
Total x-ray score, mean (SD) | 253 | 7.5 (9.7) | 253 | 6.7 (8.8) | 506 | 7.1 (9.2) |
Erosion score, mean (SD) | 253 | 5.4 (6.1) | 253 | 4.8 (5.4) | 506 | 5.1 (5.8) |
Joint-space narrowing score, mean (SD) | 253 | 2.1 (4.2) | 253 | 1.9 (4.0) | 506 | 2.0 (4.1) |