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Table 2 Crosstabulations of DMARD and Prednisolone treatment in the Never and Ever erosion groups over 8 years

From: Erosion-free rheumatoid arthritis: clinical and conceptional implications—a BARFOT study

 

Never erosions

Ever erosions

Diff

n = 144

n = 464

N (%)

SR*

N (%)

SR*

p- value

Treatment start

No DMARD No Pred

22 (15)

≥ + 2

33 (7)

 

0.003

cDMARDs

104 (72)

 

394 (85)

 

bDMARDs

6 (4)

 

8 (2)

 

Pred only

12 (8)

 

29 (6)

 

Treatment 0.5 yr

No DMARD No Pred

21 (16)

≥ + 2

37 (9)

 

0.003

cDMARDs

93 (70)

 

365 (84)

 

bDMARDs

8 (6)

≥ + 2

9 (2)

 

Pred only

10 (8)

 

22 (5)

 

Treatment 1 yr

No DMARD No Pred

30 (21)

≥ + 2

40 (9)

 

0.001

cDMARDs

96 (68)

 

379 (84)

 

bDMARDs

9 (6)

 

20 (4)

 

Pred only

7 (5)

 

11 (2)

 

Treatment 2 yrs

No DMARD No Pred

35 (26)

≥ + 2

45 (10)

≤ − 2

0.001

cDMARDs

80 (58)

≤ − 2

349 (78)

 

bDMARDs

10 (7)

 

36 (8)

 

Pred only

12 (9)

≥  + 2

16 (4)

 

Treatment 5 yrs

No DMARD No Pred

54 (39)

≥  + 2

68 (15)

≤ − 2

0.001

cDMARDs

61 (44)

≤ − 2

303 (68)

 

bDMARDs

14 (10)

 

61 (14)

 

Pred only

9 (7)

 

14 (3)

 

Treatment 8 yrs

No DMARD No Pred

50 (35)

≥ +2

81 (18)

 

0.001

cDMARDs

74 (52)

 

299 (65)

 

bDMARDs

7 (5)

≤ − 2

58 (13)

 

Pred only

12 (8)

 

19 (4)

 
  1. *SR—Standardized residual: A SR ≥ + 2 or ≤ − 2 is judged to be significant
  2. DMARD: disease modifying anti-rheumatic drug, Pred; prednisolone, cDMARD: conventional DMARD, bDMARD: biologic DMARD, yr; year, yrs; years