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Table 4 Comparison of clinical and laboratory characteristics of SLE patients

From: Association of lipoproteins and thyroid hormones with cognitive dysfunction in patients with systemic lupus erythematosus

SLE characteristics Low Cognition (n = 48) High Cognition (n = 33) P Value
Clinical characteristics
 Globulin, mg/dL 28.18 (±7.97) 27.94 (±6.59) 0.764
 Albumin, mg/dL 31.76 (±5.79) 34.91 (±4.13) < 0.01**
 24-h urine protein, (g/24 h) 1.97 (±2.59) 1.88 (±3.11) 0.433
 C3 Levels, mg/dL 0.66 (±0.32) 0.77 (±0.29) 0.143
 C4 Levels, mg/dL 0.12 (±0.08) 0.14 (±0.06) 0.323
 LDL-C (mmol/L) 2.77 (±1.37) 2.61 (±1.10) 0.590
 HDL-C (mmol/L) 1.12 (±0.39) 1.33 (±0.55) 0.051
 CRP (mg/dL) 12.36 (±14.00) 11.95 (±16.98) 0.869
 D-dimer (mg/dL) 1.74 (±1.28) 0.75 (±0.82) < 0.001***
 Cr (μmol/L) 86.95 (±80.42) 66.07 (±36.13) 0.200
 BUN (mmol/L) 8.04 (±5.66) 7.07 (±4.69) 0.491
 UA (μmol/L) 362.20 (±129.73) 339.38 (±142.41) 0.523
 GFR (mL/min/1.73 m2) 117.37 (±56.97) 140.31 (±83.36) 0.223
 ESR (mm/hour) 50.53 (±32.03) 42.59 (±28.74) 0.271
 PLT (109/L) 149.32 (±79.69) 176.09 (±90.84) 0.099
 TSH (mU/L) 2.78 (±2.31) 2.69 (±2.21) 0.830
 FT3 Levels (pmol/L) 3.20 (±1.03) 3.71 (±1.06) < 0.05*
 FT4 Levels (pmol/L) 12.51 (±3.43) 14.97 (±2.14) < 0.05*
Blood Cells
 Erythrocyte, (%) 68.66 (±118.01) 40.23 (±66.60) 0.419
 WBC, (109/L) 4.73 (±2.42) 5.43 (±3.62) 0.255
 CD3+ cells, (%) 0.73 (±0.50) 0.67 (±0.40) 0.605
 CD3 + CD4+ cells, (%) 0.33 (±0.22) 0.30 (±0.23) 0.591
 CD3 + CD8+ cells, (%) 0.39 (±0.29) 0.36 (±0.19) 0.563
 B cells, (%) 0.15 (±0.16) 0.10 (±0.13) < 0.05*
 NK cells, (%) 0.06 (±0.06) 0.06 (±0.04) 0.929
Autoantibodies
 Anti-dsDNA antibodies, U/mL 746.12 (±441.82) 314.56 (±223.99) < 0.05*
 Anti-Sm antibodies, n (%) 10 (21.28%) 8 (24.24%) 0.754
 Anti-RNP antibodies, n (%) 16 (34.04%) 13 (39.39%) 0.624
 Anti-SSA antibodies, n (%) 19 (40.43%) 14 (42.42%) 0.858
 Anti-SSB antibodies, n (%) 4 (8.51%) 2 (6.06%) 1.000
 Anti-Rib-P, n (%) 10 (21.28%) 11 (33.33%) 0.228
 Anti-β2-GPI, n (%) 1 (2.13%) 0 (0%) 1.000
 IgM (mg/dL) 1.13 (±0.72) 0.76 (±0.41) < 0.01**
 IgG (mg/dL) 14.52 (±6.79) 12.56 (±5.34) 0.172
 IgA (mg/dL) 2.49 (±1.60) 2.56 (±1.19) 0.857
 IgE (mg/dL) 0.26 (±0.44) 0.23 (±0.41) 0.620
  1. Data are expressed as number (percentage), or mean ± standard deviation (SD) values. P values are based on independent sample t-test and Chi-square test for normally distributed variables. *P < 0.05, **P < 0.01, *** P < 0.005, vs. Low Cognition. The Graph Pad Prism 7.0 and SPSS Statistics 16.0 software were used for statistical analysis