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  1. VEXAS syndrome (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic syndrome) is a recently described syndrome caused by a somatic missense variant at the methionine-41 (p.(Met41)) position in the ubiquit...

    Authors: Matheus V. M. B. Wilke, Eva Morava-Kozicz, Matthew J. Koster, Christopher T. Schmitz, Shannon Kaye Foster, Mrinal Patnaik, Kenneth J. Warrington, Eric W. Klee and Filippo Pinto e Vairo
    Citation: BMC Rheumatology 2022 6:54
  2. Rheumatoid arthritis (RA) is a chronic inflammatory arthritis which can cause joint damage and reduced quality of life. Early treatment of RA within 3 months of symptom onset is associated with improved clinic...

    Authors: Gwenda Simons, Nour Ismail, Karanbir Sandhu, Christian D. Mallen, Rebecca J. Stack, Sarah Pontefract, Karim Raza and Marie Falahee
    Citation: BMC Rheumatology 2022 6:50
  3. Psoriatic arthritis can cause pain, disability, and permanent joint damage. This can lead to impairments in work and social participation. Little is known about the extent of these impairments in routine pract...

    Authors: Tamara W. van Hal, Michelle L. M. Mulder, Mark H. Wenink and Johanna E. Vriezekolk
    Citation: BMC Rheumatology 2022 6:49
  4. Skin thickness is a prominent clinical feature of systemic sclerosis (SSc), but there is no consensus on the cut-off for a positive tuberculin skin test (TST) size and the limitation of the TST for a diagnosis...

    Authors: Apichart So-ngern, Ajanee Mahakkanukrauh, Siraphop Suwannaroj, Ratanavadee Nanagara and Chingching Foocharoen
    Citation: BMC Rheumatology 2022 6:48
  5. Research priority setting is a useful approach to decide which unanswered questions are most worth trying to solve through research. The aim is to reduce bias in the research agenda. Traditionally, research wa...

    Authors: Emma R. Dorris, Stacey Grealis, Karmen Kegl, Norelee Kennedy, Louise Larkin, Brian Lynch, Ailis Moran, Justine O’Brien, Stephanie Skeffington, Kayleigh Slater, Rebecca Ward and Allison Willett
    Citation: BMC Rheumatology 2022 6:55
  6. B mode ultrasound (US) and shear wave elastography (SWE) are easily accessible imaging tools for idiopathic inflammatory myopathies (IIM) but require further validation against standard diagnostic procedures s...

    Authors: Shereen Paramalingam, Merrilee Needham, Sarah Harris, Susan O’Hanlon, Frank Mastaglia and Helen Keen
    Citation: BMC Rheumatology 2022 6:47

    The Correction to this article has been published in BMC Rheumatology 2022 6:72

  7. To develop and assess a prediction model for polymyalgia rheumatica (PMR) relapse within the first year of glucocorticoid (GC) treatment.

    Authors: Thomas E. Bolhuis, Diane Marsman, Frank H. J. van den Hoogen, Alfons A. den Broeder, Nathan den Broeder and Aatke van der Maas
    Citation: BMC Rheumatology 2022 6:45
  8. People living with axial Spondyloarthrtis (axSpA) have an increased risk of cardiovascular diseases, which can be reduced by regular physical activity (PA) and its subset of cardiorespiratory training (CRT). T...

    Authors: Anne-Kathrin Rausch Osthoff, Irina Nast and Karin Niedermann
    Citation: BMC Rheumatology 2022 6:40
  9. Raynaud’s phenomenon is common condition, but little is known about the natural course. The primary aim of this study was to determine the incidence, remission, and persistence proportions of Raynaud’s phenome...

    Authors: Albin Stjernbrandt, Hans Pettersson, Ronnie Lundström, Ingrid Liljelind, Tohr Nilsson and Jens Wahlström
    Citation: BMC Rheumatology 2022 6:41
  10. Autoimmune disease following COVID-19 has been studied intensely since the beginning of the pandemic. Growing evidence indicates that SARS-CoV-2 infection, by virtue of molecular mimicry can lead to an antigen...

    Authors: Karolina Anderle, Klaus Machold, Hans P. Kiener, Daniel Bormann, Konrad Hoetzenecker, Silvana Geleff, Helmut Prosch, Franco Laccone, Peter M. Heil, Peter Petzelbauer, Daniel Aletaha, Stephan Blüml and Kastriot Kastrati
    Citation: BMC Rheumatology 2022 6:42
  11. Neuropsychiatric (NP) involvement and fatigue are major problems in systemic lupus erythematosus (SLE). S100A8/A9 is a marker of inflammation and responds to therapy in SLE patients. S100A8/A9 has an immunopat...

    Authors: Kristoffer A. Zervides, Andreas Jern, Jessika Nystedt, Birgitta Gullstrand, Petra C. Nilsson, Pia C. Sundgren, Anders A. Bengtsson and Andreas Jönsen
    Citation: BMC Rheumatology 2022 6:38
  12. During the first UK COVID-19 lockdown, studies identified over half of inflammatory arthritis (IA) patients in the UK reported a worsening of emotional distress. Given the prolonged nature of the pandemic, and...

    Authors: Emma Caton, Hema Chaplin, Lewis Carpenter, Melissa Sweeney, Hsiu Yen Tung, Savia de Souza, James Galloway, Elena Nikiphorou and Sam Norton
    Citation: BMC Rheumatology 2022 6:37
  13. To develop an interdisciplinary care pathway for early rheumatoid arthritis (RA) including referral triage, diagnosis, and management.

    Authors: Xenia Gukova, Glen S. Hazlewood, Hector Arbillaga, Paul MacMullan, Gabrielle L. Zimmermann, Cheryl Barnabe, May Y. Choi, Megan R. W. Barber, Alexandra Charlton, Becky Job, Kelly Osinski, Nicole M. S. Hartfeld, Marlene W. Knott, Paris Pirani and Claire E. H. Barber
    Citation: BMC Rheumatology 2022 6:35
  14. We conducted this study to identify the influence of prolonged use of hydroxychloroquine (HCQ), glucocorticoids and other immunosuppressants (IS) on occurrence and outcome of COVID-19 in patients with autoimmu...

    Authors: Abhishek Patil, K. Chanakya, Padmanabha Shenoy, S. Chandrashekara, Vikram Haridas, Sharath Kumar, Manisha Daware, Ramya Janardana, Benzeeta Pinto, Ramaswamy Subramanian, S. Nagaraj, Yogesh Preet Singh, Shweta Singhai, Ramesh Jois, Vikramraj Jain, C. Srinivasa…
    Citation: BMC Rheumatology 2022 6:32
  15. The gold standard for skin thickness assessment in systemic sclerosis (SSc) is the modified Rodnan skin score (mRSS); however, inter- and intra-rater variation can arise due to subjective methods and inexperie...

    Authors: Patnarin Pongkulkiat, Bandit Thinkhamrop, Ajanee Mahakkanukrauh, Siraphop Suwannaroj and Chingching Foocharoen
    Citation: BMC Rheumatology 2022 6:33
  16. Gout and diabetes mellitus type 2 (DM) frequently co-exist. The pharmacological effects of metformin may include anti-inflammatory and urate lowering effects. The objective of this study was to test these effe...

    Authors: Frouwke Veenstra, Lise M. Verhoef, Merel Opdam, Alfons A. den Broeder, Wing-Yee Kwok, Inger L. Meek, Cornelia H. M. van den Ende, Marcel Flendrie and Noortje van Herwaarden
    Citation: BMC Rheumatology 2022 6:27
  17. To evaluate the efficacy for symptomatic knee and hip osteoarthritis (OA) patients of a mindfulness-based stress reduction (MBSR) program versus usual care.

    Authors: Clémentine Marais, Yujie Song, Rosanna Ferreira, Safa Aounti, Claire Duflos, Grégory Baptista and Yves-Marie Pers
    Citation: BMC Rheumatology 2022 6:46
  18. There is increasing knowledge of how individual lifestyle factors affect patients with spondyloarthritis, while studies exploring the combination of unhealthy lifestyle factors are lacking. Thus, our aim was t...

    Authors: Elisabeth Mogard, Ann Bremander and Emma Haglund
    Citation: BMC Rheumatology 2022 6:29
  19. POEMS syndrome is a rare paraneoplastic syndrome caused by plasma cell disorder almost always lambda restricted. Secondary Raynaud’s phenomenon is an overlooked skin manifestation of the disease even though it...

    Authors: Fabio Torres-Saavedra and Lina León-Sierra
    Citation: BMC Rheumatology 2022 6:26
  20. This pilot study’s primary aim was to determine if oligoclonal B cell expansion in children with Juvenile Dermatomyositis (JDM) predicts response to Rituximab therapy. We evaluated: (1) tissue B cell depletion...

    Authors: Elisa Ochfeld, Victoria Hans, Wil Marin, Najah Ahsan, Gabrielle Morgan, Lauren M. Pachman and Amer Khojah
    Citation: BMC Rheumatology 2022 6:36
  21. The Invalidation Illness Inventory (3*I) is an instrument that assesses invalidation (including discounting and lack of understanding dimensions) experienced by patients with rheumatic disorders. This study ai...

    Authors: Banafsheh Ghavidel-Parsa, Mohammad-Javad Khosousi, Sepehr Tohidi, Ali Bidari, Saman Soltani, Habib Zayeni and Ali Montazeri
    Citation: BMC Rheumatology 2022 6:23
  22. Rheumatoid arthritis (RA) is an inflammatory disease that is characterized by the overproduction of cytokines. Among the newly discovered cytokines are the adipokines which are primarily produced by and releas...

    Authors: Marjan Taherian, Simin Almasi, Saber Mehdizadeh, Banafshe Fazeli, Mahsa Kalantari, Paria Bayati, Salar Pashangzadeh and Nazanin Mojtabavi
    Citation: BMC Rheumatology 2022 6:25
  23. Previous research has provided evidence for cognitive dysfunction as a common symptom of systemic lupus erythematosus (SLE). In light of this, the primary goal of this study was to investigate how cognitive im...

    Authors: L. Langensee, J. Mårtensson, A. Jönsen, K. Zervides, A. Bengtsson, J. Nystedt, B. Cannerfelt, P. Nilsson, P. Mannfolk, J. Lätt, T. Rumetshofer and P. C. Sundgren
    Citation: BMC Rheumatology 2022 6:22
  24. Rheumatoid arthritis (RA) is a heterogeneous disease with established poor prognostic factors such as seropositivity, joint damage, and high disease activity at an early, treatment-naïve stage of disease. Howe...

    Authors: Patrick Durez, Rene Westhovens, Femke Baeke, Yedid Elbez, Sofie Robert and Harris A. Ahmad
    Citation: BMC Rheumatology 2022 6:24
  25. Studying health-related quality of life (HRQoL) and treatment satisfaction have helped in understanding how to optimize rheumatoid arthritis (RA) treatment outcomes and find ways to alleviate signs and symptom...

    Authors: Heba Abu Hamdeh, Samah W. Al-Jabi, Amer Koni and Sa’ed H. Zyoud
    Citation: BMC Rheumatology 2022 6:19
  26. Dermatomyositis belongs to an infrequent group of diseases predominantly found in patients older than 40 years old and is characterized by dermal and muscular findings. This disease presents itself as proximal...

    Authors: Adolfo Camargo Coronel, Francisco Javier Jiménez Balderas, Horacio Quiñones Moya, Mario Raúl Hernández Zavala, Pedro Mandinabeitia Rodríguez, José Ramiro Hernández Vázquez, Sandy Zamora Zarco and Sergio De Jesús Aguilar Castillo
    Citation: BMC Rheumatology 2022 6:20
  27. There are many FDA-approved corticosteroid preparations available for intra-articular injection, however triamcinolone hexacetonide is not one of them. It was the intraarticular drug of choice among pediatric ...

    Authors: Angela Chun, Lutfiyya N. Muhammad and Deirdre De Ranieri
    Citation: BMC Rheumatology 2022 6:18
  28. Culture-negative infective endocarditis (IE) constitutes approximately 10% of all cases of IE. Bartonella endocarditis is a common cause of culture-negative endocarditis and is associated with a high mortality...

    Authors: Arani Vivekanantham, Rikesh Patel, Petra Jenkins, Gavin Cleary, David Porter, Fareed Khawaja and Eoghan McCarthy
    Citation: BMC Rheumatology 2022 6:16
  29. Nemaline myopathies are congenital or acquired muscle disorders that typically present in childhood but can occasionally occur in adults with underlying malignant, infectious or autoimmune disorders. There is ...

    Authors: Christina Vogel, Poonam Manwani, Marcia E. Cornford and Emil R. Heinze
    Citation: BMC Rheumatology 2022 6:21
  30. The PROMIS Preference score (PROPr) is a new generic preference-based health-related quality of life (HRQoL) score that can be used as a health state utility (HSU) score for quality-adjusted life years (QALYs)...

    Authors: C. P. Klapproth, F. Fischer, M. Merbach, M. Rose and A. Obbarius
    Citation: BMC Rheumatology 2022 6:15
  31. There is increasing research focus on prediction and prevention of rheumatoid arthritis (RA). Information about risk of RA is increasingly available via direct-to-consumer testing. However, there is limited un...

    Authors: Juhi Singhal, Imogen Wells, Gwenda Simons, Sabine Wöhlke, Karim Raza and Marie Falahee
    Citation: BMC Rheumatology 2022 6:14
  32. Although many studies have reported the predictors of fractures in patients with rheumatoid arthritis (RA) who are not receiving anti-osteoporotic treatments or who are receiving unspecified treatments, studie...

    Authors: Yuji Kishimoto, Yoshihiro Kato, Manami Uemura and Koji Kuranobu
    Citation: BMC Rheumatology 2022 6:8
  33. Over recent years the lack of patient involvement in the design, set-up and implementation of clinical research studies has been well recognised; as such there has been a drive within research communities to i...

    Authors: Hannah Jethwa, Melanie Brooke, Andrew Parkinson, Emma Dures and Nicola J. Gullick
    Citation: BMC Rheumatology 2022 6:13
  34. Shrinking lung syndrome (SLS) is a rare manifestation of systemic lupus erythematosus (SLE) characterized by decreased lung volumes and diaphragmatic weakness in a dyspneic patient. Chest wall dysfunction seco...

    Authors: Flavie Roy, Pat Korathanakhun, Jason Karamchandani, Bruno-Pierre Dubé, Océane Landon-Cardinal, Nathalie Routhier, Caroline Peyronnard, Rami Massie, Valérie Leclair, Alain Meyer, Josiane Bourré-Tessier, Minoru Satoh, Marvin J. Fritzler, Jean-Luc Senécal, Marie Hudson, Erin K. O’Ferrall…
    Citation: BMC Rheumatology 2022 6:11
  35. Behcet’s disease (BD) as a chronic inflammatory condition that affects the eyes, skin, central nervous system, gastrointestinal tract and vessels. According to the literature, the exact value of C-reactive pro...

    Authors: Amirhossein Parsaei, Soroush Moradi, Maryam Masoumi, Fereydoun Davatchi, Anahita Najafi, Ashkan Mohammadi Kooshki, Abdolkarim Hajighadery, Massoomeh Akhlaghi, Tahereh Faezi and Hoda Kavosi
    Citation: BMC Rheumatology 2022 6:9
  36. Malignant pleural mesothelioma (MPM) is a rare and aggressive tumour with an overall poor prognosis. In October 2020, first line treatment with the PD-1 antagonist nivolumab and the CTLA-4 antagonist ipilimuma...

    Authors: Joanna Kefas, Catherine Harwood, Myles J. Lewis and Peter Szlosarek
    Citation: BMC Rheumatology 2022 6:10
  37. Drug coverage policies that incentivize switching patients from originator to biosimilar products may result in significant health care savings. Our study aimed to detect early impacts on health services utili...

    Authors: Anat Fisher, Jason D. Kim, Greg Carney and Colin Dormuth
    Citation: BMC Rheumatology 2022 6:5
  38. Estimating the burden of rheumatic diseases (RDs) requires proper evaluation of its lethal and nonlethal consequences. In Colombia, it is possible to find local data and Global Burden of Disease (GBD) reports ...

    Authors: Francy-Milena Cuervo, Ana M. Santos, John Londono, José-Ignacio Angarita, Juan C. Rueda, Rodrigo Giraldo-Bustos, Jesús Giovanny Ballesteros-Muñoz, Eugenia-Lucia Saldarriaga, Diana Padilla-Ortiz, Viviana Reyes-Martinez, Ingris Peláez-Ballestas, Diana Diaz-Jiménez, Pedro Santos-Moreno, Carlos E. Pinzón and Carlos Castañeda-Orjuela
    Citation: BMC Rheumatology 2022 6:7
  39. The Ankylosing Spondylitis Association of Switzerland (SVMB) aimed to implement physical activity recommendations (PAR) within their exercise groups (EGs). The PAR promote exercise in all fitness dimensions at...

    Authors: Anne-Kathrin Rausch Osthoff, Theodora P. M. Vliet Vlieland, André Meichtry, Leti van Bodegom-Vos, Beatrice Topalidis, Stefan Büchi, Irina Nast, Adrian Ciurea and Karin Niedermann
    Citation: BMC Rheumatology 2022 6:12
  40. Rheumatoid arthritis is a complex multifactorial chronic disease, the importance of human leukocytic antigen (HLA) as a major genetic risk factor for rheumatoid arthritis was studied worldwide. The objective o...

    Authors: Niaz Albarzinji, Sherzad Ali Ismael and Dashty Albustany
    Citation: BMC Rheumatology 2022 6:4
  41. Previous research has shown an unclear and inconsistent association between fatigue and disease activity in patients with rheumatoid arthritis (RA). The aim of this study was to explore differences in “between...

    Authors: Grada A. Versteeg, Peter M. ten Klooster and Mart A. F. J. van de Laar
    Citation: BMC Rheumatology 2022 6:3

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