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  1. Inflammation of patients joints with severe disease activity of rheumatoid arthritis (RA) has already been visualized and quantified by 2-[18F]fluoro-2-deoxy-D-glucose positron emission computed tomography ([18F]...

    Authors: Charline Rinkin, Pacôme Fosse, Olivier Malaise, Nathalie Chapelier, Jil Horrion, Laurence Seidel, Adelin Albert, Roland Hustinx and Michel G. Malaise
    Citation: BMC Rheumatology 2021 5:31
    Content type: Research article Published on:

  2. Vasculitides comprise a group of rare diseases which affect less than 5 in 10.000 individuals. Most types of vasculitis can become organ- and life-threatening and are characterized by chronicity, high morbidit...

    Authors: Christof Iking-Konert, Pia Wallmeier, Sabrina Arnold, Sabine Adler, Kirsten de Groot, Bernhard Hellmich, Bimba F. Hoyer, Konstanze Holl-Ulrich, Gabriele Ihorst, Margit Kaufmann, Ina Kötter, Ulf Müller-Ladner, T. Magnus, Jürgen Rech, Fabian Schubach, Hendrik Schulze-Koops…
    Citation: BMC Rheumatology 2021 5:40
    Content type: Study protocol Published on:

  3. Risk of myocardial infarction (MI) is elevated in ankylosing spondylitis and psoriatic arthritis (AS/PsA) compared to the general population. We evaluated the risk of MI related to the use of tumor necrosis fa...

    Authors: Rachael Stovall, Christine Peloquin, David Felson, Tuhina Neogi and Maureen Dubreuil
    Citation: BMC Rheumatology 2021 5:36
    Content type: Research Published on:

  4. Anti-synthetase syndrome is the collection of myositis and/or interstitial lung disease with the presence of various antibodies directed against an aminoacyl transfer RNA synthetase. Anti Jo − 1 antibody is th...

    Authors: C. T. Rosa, A. S. Thilakarathne, L. A. Senevirathne, A. Wijeyeratna and D. Munidasa
    Citation: BMC Rheumatology 2021 5:25
    Content type: Case report Published on:

  5. Our knowledge of immune-mediated inflammatory disease (IMID) aetiology and pathogenesis has improved greatly over recent years, however, very little is known of the factors that trigger disease relapses (flare...

    Authors: Fiona Rayner, Amy E. Anderson, Kenneth F. Baker, Christopher D. Buckley, Bernard Dyke, Sally Fenton, Andrew Filer, Carl S. Goodyear, Catharien M. U. Hilkens, Shaun Hiu, Sean Kerrigan, Mariola Kurowska-Stolarska, Fiona Matthews, Iain McInnes, Wan-Fai Ng, Arthur G. Pratt…
    Citation: BMC Rheumatology 2021 5:22
    Content type: Study protocol Published on:

  6. Research on adherence interventions in rheumatology is limited by methodological issues, particularly heterogeneous outcomes. We aimed to describe researchers’ experiences with conducting interventional studie...

    Authors: Shahrzad Salmasi, Ayano Kelly, Susan J. Bartlett, Maarten de Wit, Lyn March, Allison Tong, Peter Tugwell, Kathleen Tymms, Suzanne Verstappen and Mary A. De Vera
    Citation: BMC Rheumatology 2021 5:26
    Content type: Research article Published on:

  7. Despite progress that has been made in the treatment of many immune-mediated inflammatory diseases (IMIDs), there remains a need for improved treatments. Randomised controlled trials (RCTs) provide the highest...

    Authors: Michael J. Grayling, Theophile Bigirumurame, Svetlana Cherlin, Luke Ouma, Haiyan Zheng and James M. S. Wason
    Citation: BMC Rheumatology 2021 5:21
    Content type: Research article Published on:

  8. Pain and fatigue are persistent problems in people with rheumatoid arthritis. Central sensitisation (CS) may contribute to pain and fatigue, even when treatment has controlled inflammatory disease. This study ...

    Authors: Onosi S. Ifesemen, Daniel F. McWilliams, Eamonn Ferguson, Richard Wakefield, Kehinde Akin-Akinyosoye, Deborah Wilson, Dorothy Platts, Susan Ledbury and David A. Walsh
    Citation: BMC Rheumatology 2021 5:23
    Content type: Study protocol Published on:

  9. Patients with Systemic Lupus Erythematosus (SLE) often experience pain and other symptoms that negatively impact quality of life. Interventions that enhance the use of behavioral and cognitive coping strategie...

    Authors: Kelli D. Allen, Tyler Beauchamp, Christine Rini, Francis J. Keefe, Kim L. Bennell, Rebecca J. Cleveland, Kimberlea Grimm, Katie Huffman, David G. Hu, Andres Santana, Shruti Saxena Beem, Julie Walker and Saira Z. Sheikh
    Citation: BMC Rheumatology 2021 5:20
    Content type: Research article Published on:

  10. Neuropsychiatric manifestations occur in up to 75% of adult systemic lupus erythematosus (SLE) patients and are one of the major causes of death in SLE patients. Cognitive dysfunction is a typical clinical fea...

    Authors: Li Lu, Wei Kong, Kangxing Zhou, Jinglei Chen, Yayi Hou, Huan Dou and Jun Liang
    Citation: BMC Rheumatology 2021 5:18
    Content type: Research article Published on:

  11. Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a condition characterized by sterile bone inflammation, usually occurring in childhood. Although the etiology remains unclear, this condition has been assoc...

    Authors: Hon Yan Ng, Orlee R. Guttman and Lori B. Tucker
    Citation: BMC Rheumatology 2021 5:16
    Content type: Case report Published on:

  12. Polyarteritis nodosa is a type of vasculitis affecting medium- and small-sized arteries that has been associated with hepatitis B but does not have an established relationship with autoimmune hepatitis. Here w...

    Authors: Freda Kennedy, Rachel Kapelow, Bilge D. Kalyon, Nitzan C. Roth, Arvind Rishi and Maria-Louise Barilla-LaBarca
    Citation: BMC Rheumatology 2021 5:17
    Content type: Case report Published on:

  14. Psoriatic arthritis (PsA) presents a unique clinical challenge. Affecting joints, skin, nails, and other organs, it is associated with various comorbidities and has a significant impact on quality of life, soc...

    Authors: Gareth T. Jones, Gary J. Macfarlane, Karen Forrest Keenan, Paul McNamee, Aileen R. Neilson, Stefan Siebert, A. David Burden, Lesley Kay and Philip S. Helliwell
    Citation: BMC Rheumatology 2021 5:19
    Content type: Study protocol Published on:

  15. Fibromyalgia is characterized by chronic widespread pain, and more than half of patients with fibromyalgia report that weather-related variables aggravate their symptoms. However, the differences in actual sym...

    Authors: Kazuhiro Hayashi, Kenji Miki, Noriyuki Hayashi, Ryota Hashimoto and Masao Yukioka
    Citation: BMC Rheumatology 2021 5:14
    Content type: Research article Published on:

  16. The self-reported Health Assessment Questionnaire (HAQ) is specifically designed to assess disability in arthritic patients. In many studies women report higher functional disability than men. The reasons for ...

    Authors: Sidona-Valentina Bala, Maria L. E. Andersson, Kristina Forslind, Björn Svensson and Ingiäld Hafström
    Citation: BMC Rheumatology 2021 5:13
    Content type: Research article Published on:

  17. Adult onset Still’s disease (AOSD) is a rare inflammatory disorder that classically presents with high spiking fevers, evanescent rash, and arthritis. The diagnosis is one of exclusion and can be further compl...

    Authors: Arash Mollaeian, Jingjing Chen, Nina N. Chan, Gregory A. Nizialek and Christopher J. Haas
    Citation: BMC Rheumatology 2021 5:12
    Content type: Case report Published on:

    The Correction to this article has been published in BMC Rheumatology 2021 5:29

  19. Patients with idiopathic inflammatory myopathy and autoantibodies directed against melanoma differentiation-associated protein 5 (MDA5) characteristically have interstitial lung disease, severe cutaneous invol...

    Authors: Meghan E. Ryan, Daniel Cortez, Kelly R. Dietz, Peter Karachunski and Bryce A. Binstadt
    Citation: BMC Rheumatology 2021 5:8
    Content type: Case report Published on:

  20. B cells are critical mediators of systemic lupus erythematosus (SLE) and lupus nephritis (LN), and antinuclear antibodies can be found in the serum of approximately 98% of patients with SLE. Spleen tyrosine ki...

    Authors: Christopher W. Pohlmeyer, Ching Shang, Pei Han, Zhi-Hua Cui, Randall M. Jones, Astrid S. Clarke, Bernard P. Murray, David A. Lopez, David W. Newstrom, M. David Inzunza, Franziska G. Matzkies, Kevin S. Currie and Julie A. Di Paolo
    Citation: BMC Rheumatology 2021 5:15
    Content type: Research article Published on:

  22. Pyoderma gangrenosum (PG) is an uncommon, idiopathic, ulcerative neutrophilic dermatosis. In many cases, PG is associated with a wide variety of different disorders but SLE in association with PG is relatively...

    Authors: Sing Chiek Teoh, Chun Yang Sim, Seow Lin Chuah, Victoria Kok and Cheng Lay Teh
    Citation: BMC Rheumatology 2021 5:7
    Content type: Case report Published on:

  23. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Ruth E. Costello, Antonia Marsden, Mohammad Movahedi, Mark Lunt, Jenny H. Humphreys, Richard Emsley and William G. Dixon
    Citation: BMC Rheumatology 2021 5:11
    Content type: Correction Published on:

    The original article was published in BMC Rheumatology 2020 4:4

  25. Low dose methotrexate toxicity rarely occurs, but may present with severe complications, such as pancytopenia, hepatotoxicity, mucositis, and pneumonitis. Known risk factors for methotrexate toxicity include d...

    Authors: Miguel A. Jara-Palacios, William Chun and Nomi L. Traub
    Citation: BMC Rheumatology 2021 5:5
    Content type: Case report Published on:

  26. Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that causes chronic synovitis, resulting in progressive joint destruction and functional disability and affects approximately 400,000 people in t...

    Authors: Ernest Choy, Lara Groves, Daniel Sugrue, Michael Hurst, John Houghton, Srinivasan Venkatachalam, Yusuf I. Patel, James R. Maxwell, Kevin G. Pollock and Sadie Henning
    Citation: BMC Rheumatology 2021 5:3
    Content type: Research article Published on:

  27. Fictional portrayals of illness and medical management in film and television can reflect and perpetuate cultural stereotypes about illness. The aim of this study was to analyse fictional depictions of gout in...

    Authors: Christina Derksen, Rachel Murdoch, Keith J. Petrie and Nicola Dalbeth
    Citation: BMC Rheumatology 2021 5:4
    Content type: Research article Published on:

  28. The diagnosis of Behçet disease (BD) is challenging in many cases. The purpose of this study was to describe the clinical characteristics of patients at a referral BD clinic.

    Authors: Mina Kiafar, Seyedeh Tahereh Faezi, Amir Kasaeian, Azarakhsh Baghdadi, Sahar Kakaei, Seyed Ali Mousavi, Mohammad Nejadhosseinian, Farhad Shahram, Seyedeh Zahra Ghodsi, Hormoz Shams and Fereydoun Davatchi
    Citation: BMC Rheumatology 2021 5:2
    Content type: Research article Published on:

  29. The activation of antigen specific T cells during an immune response is a tightly regulated process at the level of both costimulatory and coinhibitory receptors. One such coinhibitory receptor or checkpoint i...

    Authors: Mary Canavan, Achilleas Floudas, Douglas J. Veale and Ursula Fearon
    Citation: BMC Rheumatology 2021 5:1
    Content type: Review Published on:

  30. Rheumatoid arthritis (RA) is characterized by systemic inflammation and bone and muscle loss. Recent research showed that obesity facilitates inflammation, but it is unknown if obesity also increases the risk ...

    Authors: Andreas Friedberger, Camille Figueiredo, Tobias Bäuerle, Georg Schett and Klaus Engelke
    Citation: BMC Rheumatology 2020 4:72
    Content type: Research article Published on:

  31. Pain is the clinical hallmark of patients in patients with autoinflammatory diseases (AID) caused by variants of the NLRP3-, MEFV- or TNFRSF1A gene. However, no systematical analysis of the clinical and psycholog...

    Authors: Elisabeth Mulazzani, Nicole Zolyniak, Elisabeth Noe, Matthias Mulazzani, Shahnaz Christina Azad, Tania Kümpfel and Eduard Kraft
    Citation: BMC Rheumatology 2020 4:71
    Content type: Research article Published on:

  32. Nationally representative data on burden of musculoskeletal conditions (MSK) in Bangladesh are not available. The objective of this study was to determine the prevalence of MSK conditions and related disabilit...

    Authors: Ahmad Zahid-Al-Quadir, M. Mostafa Zaman, Shamim Ahmed, Mahfuzur Rahman Bhuiyan, Md Mujibur Rahman, Ismail Patwary, Bidhu Bhushan Das, Shaikh Amir Hossain, Sujat Paul, Abu Shahin, Moshiur Rahman and Syed Atiqul Haq
    Citation: BMC Rheumatology 2020 4:69
    Content type: Research article Published on:

  33. Antineutrophil cytoplasmic antibodies (ANCA) and Anti-glomerular basement membrane (GBM) antibodies often induce rapidly progressive glomerulonephritis (RPGN). Some reports have demonstrated RPGN with the sequ...

    Authors: Mikiya Kato, Risa Wakiya, Tomohiro Kameda, Kousuke Inoue, Tadashi Sofue, Yusuke Ushio, Koichi Sugihara, Shusaku Nakashima, Hiromi Shimada, Mai Mahmoud Fahmy Mansour, Norimitsu Kadowaki and Hiroaki Dobashi
    Citation: BMC Rheumatology 2020 4:68
    Content type: Case report Published on:

  34. Takayasu’s arteritis (TA) is a granulomatous, large vessel vasculitis with a preponderance for young women. The inflammation results in disruption of the arterial endothelium causing stenosis, endoluminal thro...

    Authors: Shania Niromi Gunasekera, Chirath Madurapperuma, Nilusha Weerasooriya, Harindra Karunathilake and Ananda Jayanaga
    Citation: BMC Rheumatology 2020 4:66
    Content type: Case report Published on:

  35. Patients with rheumatoid arthritis (RA) have high mortality risk and are frequently treated in intensive care units (ICUs).

    Authors: Toshifumi Fujiwara, Kentaro Tokuda, Kenta Momii, Kyohei Shiomoto, Hidetoshi Tsushima, Yukio Akasaki, Satoshi Ikemura, Jun-ichi Fukushi, Jun Maki, Noriyuki Kaku, Tomohiko Akahoshi, Tomoaki Taguchi and Yasuharu Nakashima
    Citation: BMC Rheumatology 2020 4:64
    Content type: Research article Published on:

  36. Vascular cell adhesion molecule-1 (VCAM-1) is involved in the progression of glomerular and tubulointerstitial injury in lupus nephritis (LN) and can be easily assessed in urine. The aim of this study was to a...

    Authors: Andrese Aline Gasparin, Nicole Pamplona Bueno de Andrade, Vanessa Hax, Penélope Esther Palominos, Marina Siebert, Romulo Marx, Pedro Guilherme Schaefer, Francisco Veríssimo Veronese and Odirlei André Monticielo
    Citation: BMC Rheumatology 2020 4:67
    Content type: Research article Published on:

  37. Reddit is a highly visited social news and discussion website where individuals anonymously ask questions, post opinions and share experiences, which provide a valuable pool of publicly available data. Our obj...

    Authors: Jamie Y. E. Park, Alyssa M. Howren, Eileen Davidson and Mary A. De Vera
    Citation: BMC Rheumatology 2020 4:62
    Content type: Research article Published on:

  39. The mixed cryoglobulinemia (MC) syndrome is a systemic inflammatory syndrome that causes small-to-medium vessel vasculitis due to cryoglobulin-containing immune complexes most commonly caused by chronic hepati...

    Authors: Nasam Alfraji, Vandan D. Upadhyaya, Christopher Bekampis and Halyna Kuzyshyn
    Citation: BMC Rheumatology 2020 4:58
    Content type: Case report Published on:

  40. The objectives of this study were to describe the profile of ankylosing spondylitis (AS) patients treated with either infliximab (IFX) or subcutaneous golimumab (GLM) treatment in Canadian routine care setting...

    Authors: Proton Rahman, Michael Starr, Derek Haaland, Louis Bessette, Michelle Teo, Emmanouil Rampakakis, Allen J. Lehman and Francois Nantel
    Citation: BMC Rheumatology 2020 4:56
    Content type: Research article Published on:

  41. Psoriasis is a chronic inflammatory disease of the skin affecting 2–3% of UK population. 30% of people affected by psoriasis will develop a distinct form of arthritis within 10 years of the skin condition onse...

    Authors: Jesus Miguens Blanco, Federica Borghese, Neil McHugh, Peter Kelleher, Raj Sengupta, Julian R. Marchesi and Sonya Abraham
    Citation: BMC Rheumatology 2020 4:60
    Content type: Study protocol Published on:

  42. The B cell chemoattractant CXCL13 is a promising biomarker in rheumatoid arthritis (RA), with a plausible role in supporting diagnosis, monitoring disease activity and as a prognostic value. It is a key chemok...

    Authors: Katie Bechman, Anthony Dalrymple, Charles Southey-Bassols, Andrew P. Cope and James B. Galloway
    Citation: BMC Rheumatology 2020 4:70
    Content type: Research article Published on:

  43. Different proportions of musculoskeletal or autoimmune manifestations associated with COVID-19 have been reported in literature. We performed a systematic review and meta-analysis with the aim of assessing the...

    Authors: Jacopo Ciaffi, Riccardo Meliconi, Piero Ruscitti, Onorina Berardicurti, Roberto Giacomelli and Francesco Ursini
    Citation: BMC Rheumatology 2020 4:65
    Content type: Research article Published on:

  44. Access to multidisciplinary pain treatment facilities (MPTF) is limited by extensive waiting time in many countries. However, there is a lack of knowledge about the impact of waiting time on clinical outcomes,...

    Authors: Simon Deslauriers, Jean-Sébastien Roy, Sasha Bernatsky, Debbie E. Feldman, Anne Marie Pinard, François Desmeules, Mary-Ann Fitzcharles and Kadija Perreault
    Citation: BMC Rheumatology 2020 4:59
    Content type: Research article Published on:

  45. Many patients with rheumatoid arthritis (RA) do not attain remission/low disease activity, remaining in a moderate disease activity state (MDAS) with ongoing disability and impaired quality of life (QoL). If p...

    Authors: Ian C. Scott, Julie Mount, Jane Barry and Bruce Kirkham
    Citation: BMC Rheumatology 2020 4:63
    Content type: Research article Published on:

  46. South Asians have a higher risk of cardiovascular disease (CVD). Rheumatoid arthritis (RA) increases the risk of premature atherosclerosis. We investigated whether there was a substantial difference in the lev...

    Authors: Kanta Kumar, Suvrat Arya, Peter Nightingale, Tom Sheeran and Amita Aggarwal
    Citation: BMC Rheumatology 2020 4:57
    Content type: Research article Published on:

  47. Musculoskeletal ultrasound (MSUS) and the multi-biomarker disease activity (MBDA) score are outcome measures that may aid in the management of rheumatoid arthritis (RA) patients. This study evaluated tofacitin...

    Authors: Amir A. Razmjou, Jenny Brook, David Elashoff, Gurjit Kaeley, Soo Choi, Tanaz Kermani and Veena K. Ranganath
    Citation: BMC Rheumatology 2020 4:55
    Content type: Research article Published on:

  49. A large number of patients with RA do not adhere to the recommended levels of physical activity to enhance health. According to EULAR recommendations, physical activity should be part of standard care in peopl...

    Authors: Ann Bremander, Karina Malm and Maria L. Andersson
    Citation: BMC Rheumatology 2020 4:53
    Content type: Research article Published on:

  50. Blood accessible biomarkers to assess disease activity and their response to therapies in Juvenile Dermatomyositis (JDM) are urgently needed. This pilot study aims to identify serum protein biomarkers associat...

    Authors: Shefa M. Tawalbeh, Wilfredo Marin, Gabrielle A. Morgan, Utkarsh J. Dang, Yetrib Hathout and Lauren M. Pachman
    Citation: BMC Rheumatology 2020 4:52
    Content type: Research article Published on:
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BMC Rheumatology

ISSN: 2520-1026

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