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  1. There are many FDA-approved corticosteroid preparations available for intra-articular injection, however triamcinolone hexacetonide is not one of them. It was the intraarticular drug of choice among pediatric ...

    Authors: Angela Chun, Lutfiyya N. Muhammad and Deirdre De Ranieri
    Citation: BMC Rheumatology 2022 6:18
    Content type: Research Published on:

  2. Culture-negative infective endocarditis (IE) constitutes approximately 10% of all cases of IE. Bartonella endocarditis is a common cause of culture-negative endocarditis and is associated with a high mortality...

    Authors: Arani Vivekanantham, Rikesh Patel, Petra Jenkins, Gavin Cleary, David Porter, Fareed Khawaja and Eoghan McCarthy
    Citation: BMC Rheumatology 2022 6:16
    Content type: Case report Published on:

  3. Nemaline myopathies are congenital or acquired muscle disorders that typically present in childhood but can occasionally occur in adults with underlying malignant, infectious or autoimmune disorders. There is ...

    Authors: Christina Vogel, Poonam Manwani, Marcia E. Cornford and Emil R. Heinze
    Citation: BMC Rheumatology 2022 6:21
    Content type: Case report Published on:

  4. The PROMIS Preference score (PROPr) is a new generic preference-based health-related quality of life (HRQoL) score that can be used as a health state utility (HSU) score for quality-adjusted life years (QALYs)...

    Authors: C. P. Klapproth, F. Fischer, M. Merbach, M. Rose and A. Obbarius
    Citation: BMC Rheumatology 2022 6:15
    Content type: Research Published on:

  5. There is increasing research focus on prediction and prevention of rheumatoid arthritis (RA). Information about risk of RA is increasingly available via direct-to-consumer testing. However, there is limited un...

    Authors: Juhi Singhal, Imogen Wells, Gwenda Simons, Sabine Wöhlke, Karim Raza and Marie Falahee
    Citation: BMC Rheumatology 2022 6:14
    Content type: Research Published on:

  7. Although many studies have reported the predictors of fractures in patients with rheumatoid arthritis (RA) who are not receiving anti-osteoporotic treatments or who are receiving unspecified treatments, studie...

    Authors: Yuji Kishimoto, Yoshihiro Kato, Manami Uemura and Koji Kuranobu
    Citation: BMC Rheumatology 2022 6:8
    Content type: Research Published on:

  8. Over recent years the lack of patient involvement in the design, set-up and implementation of clinical research studies has been well recognised; as such there has been a drive within research communities to i...

    Authors: Hannah Jethwa, Melanie Brooke, Andrew Parkinson, Emma Dures and Nicola J. Gullick
    Citation: BMC Rheumatology 2022 6:13
    Content type: Research Published on:

  9. Shrinking lung syndrome (SLS) is a rare manifestation of systemic lupus erythematosus (SLE) characterized by decreased lung volumes and diaphragmatic weakness in a dyspneic patient. Chest wall dysfunction seco...

    Authors: Flavie Roy, Pat Korathanakhun, Jason Karamchandani, Bruno-Pierre Dubé, Océane Landon-Cardinal, Nathalie Routhier, Caroline Peyronnard, Rami Massie, Valérie Leclair, Alain Meyer, Josiane Bourré-Tessier, Minoru Satoh, Marvin J. Fritzler, Jean-Luc Senécal, Marie Hudson, Erin K. O’Ferrall…
    Citation: BMC Rheumatology 2022 6:11
    Content type: Case report Published on:

  10. Behcet’s disease (BD) as a chronic inflammatory condition that affects the eyes, skin, central nervous system, gastrointestinal tract and vessels. According to the literature, the exact value of C-reactive pro...

    Authors: Amirhossein Parsaei, Soroush Moradi, Maryam Masoumi, Fereydoun Davatchi, Anahita Najafi, Ashkan Mohammadi Kooshki, Abdolkarim Hajighadery, Massoomeh Akhlaghi, Tahereh Faezi and Hoda Kavosi
    Citation: BMC Rheumatology 2022 6:9
    Content type: Research Published on:

  11. Malignant pleural mesothelioma (MPM) is a rare and aggressive tumour with an overall poor prognosis. In October 2020, first line treatment with the PD-1 antagonist nivolumab and the CTLA-4 antagonist ipilimuma...

    Authors: Joanna Kefas, Catherine Harwood, Myles J. Lewis and Peter Szlosarek
    Citation: BMC Rheumatology 2022 6:10
    Content type: Case report Published on:

  13. Drug coverage policies that incentivize switching patients from originator to biosimilar products may result in significant health care savings. Our study aimed to detect early impacts on health services utili...

    Authors: Anat Fisher, Jason D. Kim, Greg Carney and Colin Dormuth
    Citation: BMC Rheumatology 2022 6:5
    Content type: Research Published on:

  14. Estimating the burden of rheumatic diseases (RDs) requires proper evaluation of its lethal and nonlethal consequences. In Colombia, it is possible to find local data and Global Burden of Disease (GBD) reports ...

    Authors: Francy-Milena Cuervo, Ana M. Santos, John Londono, José-Ignacio Angarita, Juan C. Rueda, Rodrigo Giraldo-Bustos, Jesús Giovanny Ballesteros-Muñoz, Eugenia-Lucia Saldarriaga, Diana Padilla-Ortiz, Viviana Reyes-Martinez, Ingris Peláez-Ballestas, Diana Diaz-Jiménez, Pedro Santos-Moreno, Carlos E. Pinzón and Carlos Castañeda-Orjuela
    Citation: BMC Rheumatology 2022 6:7
    Content type: Research Published on:

  15. The Ankylosing Spondylitis Association of Switzerland (SVMB) aimed to implement physical activity recommendations (PAR) within their exercise groups (EGs). The PAR promote exercise in all fitness dimensions at...

    Authors: Anne-Kathrin Rausch Osthoff, Theodora P. M. Vliet Vlieland, André Meichtry, Leti van Bodegom-Vos, Beatrice Topalidis, Stefan Büchi, Irina Nast, Adrian Ciurea and Karin Niedermann
    Citation: BMC Rheumatology 2022 6:12
    Content type: Research Published on:

  16. Rheumatoid arthritis is a complex multifactorial chronic disease, the importance of human leukocytic antigen (HLA) as a major genetic risk factor for rheumatoid arthritis was studied worldwide. The objective o...

    Authors: Niaz Albarzinji, Sherzad Ali Ismael and Dashty Albustany
    Citation: BMC Rheumatology 2022 6:4
    Content type: Research Published on:

  17. Previous research has shown an unclear and inconsistent association between fatigue and disease activity in patients with rheumatoid arthritis (RA). The aim of this study was to explore differences in “between...

    Authors: Grada A. Versteeg, Peter M. ten Klooster and Mart A. F. J. van de Laar
    Citation: BMC Rheumatology 2022 6:3
    Content type: Research Published on:

  18. Gout, an inflammatory condition, is characterized by the precipitation of monosodium urate crystals (MSU) in or around distal joints. The latter is caused by chronic hyperuricemia (HU)—high urate levels in the...

    Authors: Ali Alghubayshi, Alison Edelman, Khalifa Alrajeh and Youssef Roman
    Citation: BMC Rheumatology 2022 6:1
    Content type: Research Published on:

  19. We have here assessed the impact of demographic, clinical, and treatment compliance characteristics on health-related quality of life (HRQoL) of Venezuelan patients with systemic lupus erythematosus (SLE). We ...

    Authors: Fhabián S. Carrión-Nessi, María V. Marcano-Rojas, Sinibaldo R. Romero Arocha, Daniela L. Mendoza Millán, David A. Forero-Peña, Allen W. Antuarez-Magallanes, Soham Al Snih, Martín A. Rodríguez and Yurilís J. Fuentes-Silva
    Citation: BMC Rheumatology 2022 6:2
    Content type: Research Published on:

  20. Adult-onset Still’s disease (AOSD) is an autoinflammatory multi-systemic syndrome. Macrophage activation syndrome (MAS) is a potentially life-threatening complication of AOSD with a mortality rate of 10–20%. E...

    Authors: Frédéric Muench, Martin Krusche, Leif Erik Sander, Thomas Rose, Gerd-Rüdiger Burmester and Udo Schneider
    Citation: BMC Rheumatology 2021 5:60
    Content type: Case report Published on:

  21. Vitamin D deficiency is highly prevalent among patients with osteoarthritis. It is associated with joint pain, stiffness and worse physical function. Whether vitamin D deficiency is associated with osteoarthri...

    Authors: Fiona Namutebi, James Kayima and Mark Kaddumukasa
    Citation: BMC Rheumatology 2021 5:56
    Content type: Research Published on:

  23. Patient education is integral to the treatment and care of patients with rheumatoid arthritis. Change is taking place in the organisation of healthcare systems because of a demographic shift towards ageing pop...

    Authors: Line Raunsbæk Knudsen, Kirsten Lomborg, Mwidimi Ndosi, Ellen-Margrethe Hauge and Annette de Thurah
    Citation: BMC Rheumatology 2021 5:57
    Content type: Study protocol Published on:

  24. Macrophage activation syndrome (MAS) is a rare multiorgan system disorder that may present as a fatal complication of underlying rheumatological disease, including dermatomyositis.

    Authors: Marzieh Keshtkarjahromi, Sumit Chhetri, Amulya Balagani, Umm-ul-Banin B. Tayyab and Christopher J. Haas
    Citation: BMC Rheumatology 2021 5:59
    Content type: Case report Published on:

  25. Composite responder endpoints feature frequently in rheumatology due to the multifaceted nature of many of these conditions. Current analysis methods used to analyse these endpoints discard much of the data us...

    Authors: Martina McMenamin, Michael J. Grayling, Anna Berglind and James M. S. Wason
    Citation: BMC Rheumatology 2021 5:54
    Content type: Software Published on:

  26. In addition to the well-known role of vitamin D in calcium homeostasis and bone metabolism, vitamin D is important in the modulation of the immune system and inflammatory processes. Vitamin D deficiency is com...

    Authors: Rosalie Magro, Christian Saliba, Liberato Camilleri, Christian Scerri and Andrew A. Borg
    Citation: BMC Rheumatology 2021 5:53
    Content type: Research Published on:

  27. Precision medicine, as a personalized medicine approach based on biomarkers, is a booming field. In general, physicians and patients have a positive attitude toward precision medicine, but their knowledge and ...

    Authors: Sophie Ruel-Gagné, David Simonyan, Jean Légaré, Louis Bessette, Paul R. Fortin, Diane Lacaille, Maman Joyce Dogba and Laëtitia Michou
    Citation: BMC Rheumatology 2021 5:52
    Content type: Research article Published on:

  28. Improvements in the treatment of rheumatoid arthritis (RA) have made it possible to achieve treatment goals. It has been reported that both residual synovitis caused by RA and the patients’ subjective symptoms...

    Authors: Masao Nawata, Kazuki Someya, Masashi Funada, Yuya Fujita, Atsushi Nagayasu, Kazuyoshi Saito and Yoshiya Tanaka
    Citation: BMC Rheumatology 2021 5:49
    Content type: Research Published on:

  29. Patients with Rheumatoid Arthritis (RA) may experience psychological distress (depression, anxiety) in addition to their physical symptoms. People with RA may also experience disease-specific distress (DSD), r...

    Authors: Linda Silke, Othman Kirresh, Jackie Sturt and Heidi Lempp
    Citation: BMC Rheumatology 2021 5:51
    Content type: Research article Published on:

  30. Immune-mediated inflammatory diseases (IMID) are characterized by systemic inflammation affecting the joints and bodily organs. Studies examining the association between individual IMIDs and the risk of Alzhei...

    Authors: Michael J. Booth, Lindsay C. Kobayashi, Mary R. Janevic, Daniel Clauw and John D. Piette
    Citation: BMC Rheumatology 2021 5:48
    Content type: Research Published on:

  31. A growing population of older adults and improved effective treatments for inflammatory rheumatic diseases will increase the demand for more healthcare resources that already struggle with staggering outpatien...

    Authors: Alen Brkic, Jung G. Kim, Glenn Haugeberg and Andreas P. Diamantopoulos
    Citation: BMC Rheumatology 2021 5:43
    Content type: Review Published on:

  32. The purpose of this study was to determine the prevalence of musculoskeletal complaints, rheumatologic diseases, and disability among the Zoroastrian population in Iran.

    Authors: Ali Dehghan, Hossein Soleimani Salehabadi, Ahmadreza Jamshidi, Zohre Kamali, Mojgan Mali, Seyedeh Tahereh Faezi, Azarakhsh Baghdadi, Sogol Alesaeidi, Fatemeh Sahraei, Niloufar Azizi, Sanaz Zand, Sara Sadat Yasini, Maryam Namazi, Atefe Daya, Ryan Nazemian, Farimah Shamsi…
    Citation: BMC Rheumatology 2021 5:46
    Content type: Research article Published on:

  33. Management of psoriasis patients with arthralgia suffering from suspected psoriatic arthritis (PsA) requires an interdisciplinary approach involving dermatologists and rheumatologists. The aim of the study was...

    Authors: Jana Ziob, Charlotte Behning, Peter Brossart, Thomas Bieber, Dagmar Wilsmann-Theis and Valentin Sebastian Schäfer
    Citation: BMC Rheumatology 2021 5:45
    Content type: Research Published on:

  34. Educational attainment is moderately heritable and inversely associated with the risk of rheumatoid arthritis. However, the causality from educational attainment on rheumatoid arthritis remained unknown. Here,...

    Authors: Guiwu Huang, Jiahao Cai, Wenchang Li, Yanlin Zhong, Weiming Liao and Peihui Wu
    Citation: BMC Rheumatology 2021 5:47
    Content type: Research Published on:

  35. Inflammatory arthritis (IA) patients have been identified as at greater risk of severe illness from COVID-19. It is likely that lockdown restrictions (enforced by the UK government in response to the COVID-19 ...

    Authors: Emma Caton, Hema Chaplin, Lewis Carpenter, Melissa Sweeney, Hsiu Yen Tung, Savia de Souza, James Galloway, Elena Nikiphorou and Sam Norton
    Citation: BMC Rheumatology 2021 5:58
    Content type: Research Published on:

  36. We describe Raynauds phenomenon (RP), potential very early diagnosis of systemic sclerosis (VEDOSS), and systemic sclerosis (SSc) in Veterans deployed in support of Post-9/11 operations. We sought to describe ...

    Authors: Tracy M. Frech, Maureen A. Murtaugh, Megan Amuan and Mary Jo Pugh
    Citation: BMC Rheumatology 2021 5:42
    Content type: Research article Published on:

  37. Galactosialidosis (GS) is a rare inherited lysosomal storage disorder (LSD) which is characterized by a defect in the lysosomal glycoprotein catabolism. We report, for the first time, the case of a child affec...

    Authors: F. Verkuil, A. M. Bosch, P. A. A. Struijs, R. Hemke and J. M. van den Berg
    Citation: BMC Rheumatology 2021 5:41
    Content type: Case report Published on:

  38. This study aimed to investigate the hospitalisation rates and the reasons for hospitalisation in patients with polymyalgia rheumatica (PMR). Furthermore, it aimed to clarify the impact of a newly established F...

    Authors: Stavros Chrysidis, Philip Rask Lage-Hansen, Nikoletta Svendsen and Andreas P. Diamantopoulos
    Citation: BMC Rheumatology 2021 5:37
    Content type: Research Published on:

  39. Ocular manifestations are common in systemic lupus erythematosus (SLE). Retinopathy has previously been linked to disease severity and might have a significant impact on the patient’s quality of life and has a...

    Authors: Hamidreza Bashiri, Nooshin Karimi, Shayan Mostafaei, Azarakhsh Baghdadi, Mohammad Nejadhosseinian and Seyedeh Tahereh Faezi
    Citation: BMC Rheumatology 2021 5:34
    Content type: Research Published on:

  41. Patients with non-radiographic axial spondyloarthritis experience negative impacts on sleep, work productivity, and activity impairment. Ixekizumab, a monoclonal antibody selectively targeting interleukin-17A,...

    Authors: Atul Deodhar, Philip Mease, Helena Marzo-Ortega, Theresa Hunter, David Sandoval, Andris Kronbergs, Steven Lauzon, Ann Leung and Victoria Navarro-Compán
    Citation: BMC Rheumatology 2021 5:50
    Content type: Research Published on:

  42. This analysis assessed improvements in patients with radiographic axial spondyloarthritis (r-axSpA) treated with ixekizumab in the Assessment of Spondyloarthritis International Society (ASAS) treatment respons...

    Authors: Atul A. Deodhar, Philip J. Mease, Proton Rahman, Victoria Navarro-Compán, Vibeke Strand, Theresa Hunter, Rebecca Bolce, Luis Leon, Steve Lauzon and Helena Marzo-Ortega
    Citation: BMC Rheumatology 2021 5:35
    Content type: Research Published on:

  44. Eosinophilic granulomatosis with polyangiitis (EGPA) is an anti-neutrophil antibody (ANCA)-associated necrotizing vasculitis, which predominantly affects small to medium vessels, and is associated with asthma ...

    Authors: Ken-ei Sada, Atsushi Miyauchi, Daisuke Hashimoto, Riku Ino, Shigeru Nojima, Shingo Yamanaka and Masafumi Kawamura
    Citation: BMC Rheumatology 2021 5:28
    Content type: Case report Published on:

  45. Patients with axial spondyloarthritis (axSpA) may experience spinal stiffness and pain, leading to reduced physical function and quality of life. Despite the benefits of physical activity (PA) and exercise, pr...

    Authors: Jie Kie Phang, Andrew Yu Keat Khor, Yu Heng Kwan, Chin Teck Ng and Warren Fong
    Citation: BMC Rheumatology 2021 5:38
    Content type: Research Published on:

  46. Cardiovascular diseases (CVDs) are the leading cause of death in patients with rheumatoid arthritis (RA). Coronary artery calcium (CAC) score quantifies the severity of atherosclerosis. We estimated CVD risk u...

    Authors: Se Hee Kim, Sang-Heon Lee, Hae-Rim Kim and Hong Ki Min
    Citation: BMC Rheumatology 2021 5:39
    Content type: Research Published on:

  47. Elevated serum urate (SU) concentration is the central risk factor for the development of gout. The aim of this study was to examine the incidence of gout in people with low and normal SU levels (< 7.00 mg/dL).

    Authors: Philip C. Robinson, Christopher Frampton, Amanda Phipps-Green, Tuhina Neogi, Lisa Stamp, William Taylor, Tony R. Merriman and Nicola Dalbeth
    Citation: BMC Rheumatology 2021 5:33
    Content type: Research Published on:

  48. The aims of our study were two-fold. Firstly, to determine if there is an association between gout and OSA in a representative Australian adult population. Secondly, to explore associations between gout and pa...

    Authors: Julia New-Tolley, Amy C. Reynolds, Sarah L. Appleton, Tiffany K. Gill, Susan Lester, Robert J. Adams and Catherine L. Hill
    Citation: BMC Rheumatology 2021 5:30
    Content type: Research Published on:

  49. Studies suggest an increased prevalence of cognitive impairment (CI) among people with rheumatoid arthritis (RA). However, most prior studies have used convenience samples which are subject to selection biases...

    Authors: Michael J. Booth, Mary R. Janevic, Lindsay C. Kobayashi, Daniel J. Clauw and John D. Piette
    Citation: BMC Rheumatology 2021 5:24
    Content type: Research Published on:
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BMC Rheumatology

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